The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"SH3 Domains
".
FunFam 6723: Intersectin 1 isoform 8
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | M9ND00 (/IPI) M9PBF6 (/IPI) M9PDC7 (/IPI) Q1WWC9 (/IPI) Q8INU2 (/IPI) Q8T068 (/IPI) Q9VIF7 (/IPI) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of neuroblast proliferation GO:0002052
Any process that activates or increases the rate of neuroblast proliferation.
|
7 | M9ND00 (/IMP) M9PBF6 (/IMP) M9PDC7 (/IMP) Q1WWC9 (/IMP) Q8INU2 (/IMP) Q8T068 (/IMP) Q9VIF7 (/IMP) |
|
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium regualated exocytosis during synaptic transmission.
|
7 | M9ND00 (/NAS) M9PBF6 (/NAS) M9PDC7 (/NAS) Q1WWC9 (/NAS) Q8INU2 (/NAS) Q8T068 (/NAS) Q9VIF7 (/NAS) |
|
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
|
7 | M9ND00 (/IMP) M9PBF6 (/IMP) M9PDC7 (/IMP) Q1WWC9 (/IMP) Q8INU2 (/IMP) Q8T068 (/IMP) Q9VIF7 (/IMP) |
|
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
|
7 | M9ND00 (/IMP) M9PBF6 (/IMP) M9PDC7 (/IMP) Q1WWC9 (/IMP) Q8INU2 (/IMP) Q8T068 (/IMP) Q9VIF7 (/IMP) |
|
Positive regulation of protein kinase activity GO:0045860
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
|
7 | M9ND00 (/IDA) M9PBF6 (/IDA) M9PDC7 (/IDA) Q1WWC9 (/IDA) Q8INU2 (/IDA) Q8T068 (/IDA) Q9VIF7 (/IDA) |
|
Synaptic vesicle endocytosis GO:0048488
Clathrin-mediated endocytosis of presynaptic membrane that recycles synaptic vesicle membrane and its components following synaptic vesicle exocytosis. This process starts with coating of the membrane with adaptor proteins and clathrin prior to invagination and ends when uncoating has finished.
|
7 | M9ND00 (/IMP) M9PBF6 (/IMP) M9PDC7 (/IMP) Q1WWC9 (/IMP) Q8INU2 (/IMP) Q8T068 (/IMP) Q9VIF7 (/IMP) |
|
Synaptic vesicle endocytosis GO:0048488
Clathrin-mediated endocytosis of presynaptic membrane that recycles synaptic vesicle membrane and its components following synaptic vesicle exocytosis. This process starts with coating of the membrane with adaptor proteins and clathrin prior to invagination and ends when uncoating has finished.
|
7 | M9ND00 (/TAS) M9PBF6 (/TAS) M9PDC7 (/TAS) Q1WWC9 (/TAS) Q8INU2 (/TAS) Q8T068 (/TAS) Q9VIF7 (/TAS) |
|
Synaptic growth at neuromuscular junction GO:0051124
The growth of a synapse at a neuromuscular junction, the site of apposition of a motor end plate and the subneural cleft of the skeletal muscle fiber that it innervates.
|
7 | M9ND00 (/IMP) M9PBF6 (/IMP) M9PDC7 (/IMP) Q1WWC9 (/IMP) Q8INU2 (/IMP) Q8T068 (/IMP) Q9VIF7 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
7 | M9ND00 (/IDA) M9PBF6 (/IDA) M9PDC7 (/IDA) Q1WWC9 (/IDA) Q8INU2 (/IDA) Q8T068 (/IDA) Q9VIF7 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | M9ND00 (/IDA) M9PBF6 (/IDA) M9PDC7 (/IDA) Q1WWC9 (/IDA) Q8INU2 (/IDA) Q8T068 (/IDA) Q9VIF7 (/IDA) |
|
Synaptic vesicle GO:0008021
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
|
7 | M9ND00 (/IDA) M9PBF6 (/IDA) M9PDC7 (/IDA) Q1WWC9 (/IDA) Q8INU2 (/IDA) Q8T068 (/IDA) Q9VIF7 (/IDA) |
|
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
|
7 | M9ND00 (/IDA) M9PBF6 (/IDA) M9PDC7 (/IDA) Q1WWC9 (/IDA) Q8INU2 (/IDA) Q8T068 (/IDA) Q9VIF7 (/IDA) |