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CATH Superfamily 2.30.30.40

SH3 Domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
SH3 Domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4807: Rho guanine nucleotide exchange factor 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Rho guanyl-nucleotide exchange factor activity GO:0005089
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
 9 B7Z0H3 (/ISS) E1JHV3 (/ISS) M9PBG8 (/ISS) Q8IRJ2 (/ISS) Q8IRJ3 (/ISS) Q8IRJ4 (/ISS) Q9W0R9 (/ISS) Q9W0S0 (/ISS) Q9W0S2 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Melanotic encapsulation of foreign target GO:0035011
Formation of a multilayered, melanized sheath of cells around a foreign invader.
 9 B7Z0H3 (/IMP) E1JHV3 (/IMP) M9PBG8 (/IMP) Q8IRJ2 (/IMP) Q8IRJ3 (/IMP) Q8IRJ4 (/IMP) Q9W0R9 (/IMP) Q9W0S0 (/IMP) Q9W0S2 (/IMP)
Regulation of Rho protein signal transduction GO:0035023
Any process that modulates the frequency, rate or extent of Rho protein signal transduction.
 9 B7Z0H3 (/ISS) E1JHV3 (/ISS) M9PBG8 (/ISS) Q8IRJ2 (/ISS) Q8IRJ3 (/ISS) Q8IRJ4 (/ISS) Q9W0R9 (/ISS) Q9W0S0 (/ISS) Q9W0S2 (/ISS)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.