The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
SH3 Domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 19688: Actin cytoskeleton-regulatory complex protein SLA1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P32790 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P32790 (/IPI)
Ubiquitin binding GO:0043130
Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
1 P32790 (/IDA)
Endocytic adaptor activity GO:0098748
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex as a key step in receptor mediated endocytosis.
1 P32790 (/IMP)
Endocytic adaptor activity GO:0098748
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex as a key step in receptor mediated endocytosis.
1 P32790 (/IPI)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin cortical patch assembly GO:0000147
Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.
2 P32790 (/IMP) Q5ALV2 (/IMP)
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
2 P32790 (/IMP) Q5ALV2 (/IMP)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
1 Q5ALV2 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
1 Q5ALV2 (/IMP)
Negative regulation of Arp2/3 complex-mediated actin nucleation GO:0034316
Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.
1 P32790 (/IDA)
Negative regulation of Arp2/3 complex-mediated actin nucleation GO:0034316
Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.
1 P32790 (/IMP)
Negative regulation of Arp2/3 complex-mediated actin nucleation GO:0034316
Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.
1 P32790 (/IPI)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P32790 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P32790 (/IMP)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
1 P32790 (/IDA)
Site of polarized growth GO:0030427
Any part of a cell where non-isotropic growth takes place.
1 Q5ALV2 (/IDA)
Actin cortical patch GO:0030479
An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
1 P32790 (/IDA)