The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"SH3 Domains
".
FunFam 19222: NADPH oxidase activator 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Superoxide-generating NADPH oxidase activator activity GO:0016176
Increases the activity of the enzyme superoxide-generating NADPH oxidase.
|
2 | Q86UR1 (/IDA) Q8CJ00 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q86UR1 (/IPI) |
|
Superoxide-generating NADPH oxidase activator activity GO:0016176
Increases the activity of the enzyme superoxide-generating NADPH oxidase.
|
1 | Q86UR1 (/IMP) |
|
Superoxide-generating NADPH oxidase activator activity GO:0016176
Increases the activity of the enzyme superoxide-generating NADPH oxidase.
|
1 | Q8CJ00 (/ISO) |
|
Superoxide-generating NADPH oxidase activator activity GO:0016176
Increases the activity of the enzyme superoxide-generating NADPH oxidase.
|
1 | A7E3N7 (/ISS) |
|
SH3 domain binding GO:0017124
Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
|
1 | Q86UR1 (/IPI) |
|
SH3 domain binding GO:0017124
Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
|
1 | Q8CJ00 (/ISO) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q86UR1 (/IPI) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q8CJ00 (/ISO) |
|
Rac GTPase binding GO:0048365
Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
|
1 | Q86UR1 (/IPI) |
|
Rac GTPase binding GO:0048365
Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
|
1 | Q8CJ00 (/ISO) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Superoxide metabolic process GO:0006801
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
|
1 | Q8CJ00 (/IDA) |
|
Superoxide metabolic process GO:0006801
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
|
1 | Q86UR1 (/IMP) |
|
Superoxide metabolic process GO:0006801
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
|
1 | Q8CJ00 (/ISO) |
|
Superoxide metabolic process GO:0006801
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
|
1 | A7E3N7 (/ISS) |
|
Regulation of hydrogen peroxide metabolic process GO:0010310
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
|
1 | Q86UR1 (/IMP) |
|
Regulation of hydrogen peroxide metabolic process GO:0010310
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
|
1 | Q8CJ00 (/ISO) |
|
Regulation of respiratory burst GO:0060263
Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
|
1 | Q86UR1 (/IMP) |
|
Regulation of respiratory burst GO:0060263
Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
|
1 | Q8CJ00 (/ISO) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q86UR1 (/TAS) |
|
NADPH oxidase complex GO:0043020
A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.
|
1 | Q86UR1 (/IDA) |
|
NADPH oxidase complex GO:0043020
A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.
|
1 | Q8CJ00 (/ISO) |