The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"SH3 Domains
".
FunFam 19148: SH3 domain-binding protein 4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
GDP-dissociation inhibitor activity GO:0005092
Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding.
|
7 | Q1LVQ2 (/ISS) Q5U228 (/ISS) Q6NU22 (/ISS) Q6NU51 (/ISS) Q8AXQ3 (/ISS) Q921I6 (/ISS) Q9JJS5 (/ISS) |
|
GDP-dissociation inhibitor activity GO:0005092
Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding.
|
1 | Q9P0V3 (/IMP) |
|
GDP-dissociation inhibitor activity GO:0005092
Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding.
|
1 | Q921I6 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9P0V3 (/IPI) |
|
Ras GTPase binding GO:0017016
Interacting selectively and non-covalently with any member of the Ras superfamily of monomeric GTPases.
|
1 | Q9P0V3 (/IPI) |
|
Ras GTPase binding GO:0017016
Interacting selectively and non-covalently with any member of the Ras superfamily of monomeric GTPases.
|
1 | Q921I6 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q9P0V3 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q921I6 (/ISO) |
There are 24 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
7 | Q1LVQ2 (/ISS) Q5U228 (/ISS) Q6NU22 (/ISS) Q6NU51 (/ISS) Q8AXQ3 (/ISS) Q921I6 (/ISS) Q9JJS5 (/ISS) |
|
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
7 | Q1LVQ2 (/ISS) Q5U228 (/ISS) Q6NU22 (/ISS) Q6NU51 (/ISS) Q8AXQ3 (/ISS) Q921I6 (/ISS) Q9JJS5 (/ISS) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
7 | Q1LVQ2 (/ISS) Q5U228 (/ISS) Q6NU22 (/ISS) Q6NU51 (/ISS) Q8AXQ3 (/ISS) Q921I6 (/ISS) Q9JJS5 (/ISS) |
|
Negative regulation of TOR signaling GO:0032007
Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.
|
7 | Q1LVQ2 (/ISS) Q5U228 (/ISS) Q6NU22 (/ISS) Q6NU51 (/ISS) Q8AXQ3 (/ISS) Q921I6 (/ISS) Q9JJS5 (/ISS) |
|
Negative regulation of GTPase activity GO:0034260
Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.
|
7 | Q1LVQ2 (/ISS) Q5U228 (/ISS) Q6NU22 (/ISS) Q6NU51 (/ISS) Q8AXQ3 (/ISS) Q921I6 (/ISS) Q9JJS5 (/ISS) |
|
Regulation of catalytic activity GO:0050790
Any process that modulates the activity of an enzyme.
|
7 | Q1LVQ2 (/ISS) Q5U228 (/ISS) Q6NU22 (/ISS) Q6NU51 (/ISS) Q8AXQ3 (/ISS) Q921I6 (/ISS) Q9JJS5 (/ISS) |
|
Protein localization to lysosome GO:0061462
A process in which a protein is transported to, or maintained in, a location within a lysosome.
|
7 | Q1LVQ2 (/ISS) Q5U228 (/ISS) Q6NU22 (/ISS) Q6NU51 (/ISS) Q8AXQ3 (/ISS) Q921I6 (/ISS) Q9JJS5 (/ISS) |
|
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
|
7 | Q1LVQ2 (/ISS) Q5U228 (/ISS) Q6NU22 (/ISS) Q6NU51 (/ISS) Q8AXQ3 (/ISS) Q921I6 (/ISS) Q9JJS5 (/ISS) |
|
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | Q9P0V3 (/IMP) |
|
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | Q921I6 (/ISO) |
|
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | Q9P0V3 (/IMP) |
|
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | Q921I6 (/ISO) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
1 | Q9P0V3 (/IMP) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
1 | Q921I6 (/ISO) |
|
Negative regulation of TOR signaling GO:0032007
Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.
|
1 | Q9P0V3 (/IMP) |
|
Negative regulation of TOR signaling GO:0032007
Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.
|
1 | Q921I6 (/ISO) |
|
Negative regulation of GTPase activity GO:0034260
Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.
|
1 | Q9P0V3 (/IDA) |
|
Negative regulation of GTPase activity GO:0034260
Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.
|
1 | Q921I6 (/ISO) |
|
Regulation of catalytic activity GO:0050790
Any process that modulates the activity of an enzyme.
|
1 | Q9P0V3 (/IMP) |
|
Regulation of catalytic activity GO:0050790
Any process that modulates the activity of an enzyme.
|
1 | Q921I6 (/ISO) |
|
Protein localization to lysosome GO:0061462
A process in which a protein is transported to, or maintained in, a location within a lysosome.
|
1 | Q9P0V3 (/IMP) |
|
Protein localization to lysosome GO:0061462
A process in which a protein is transported to, or maintained in, a location within a lysosome.
|
1 | Q921I6 (/ISO) |
|
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
|
1 | Q9P0V3 (/IMP) |
|
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
|
1 | Q921I6 (/ISO) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
7 | Q1LVQ2 (/ISS) Q5U228 (/ISS) Q6NU22 (/ISS) Q6NU51 (/ISS) Q8AXQ3 (/ISS) Q921I6 (/ISS) Q9JJS5 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9P0V3 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q921I6 (/ISO) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q9P0V3 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q921I6 (/ISO) |