The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
SH3 Domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1098: Nervous wreck, isoform D

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 M9NE66 (/IPI) M9NF56 (/IPI) M9NFQ1 (/IPI) Q9VSU8 (/IPI) X2J8V0 (/IPI) X2JAU8 (/IPI) X2JC77 (/IPI) X2JCQ1 (/IPI) X2JGF9 (/IPI)
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
9 M9NE66 (/ISM) M9NF56 (/ISM) M9NFQ1 (/ISM) Q9VSU8 (/ISM) X2J8V0 (/ISM) X2JAU8 (/ISM) X2JC77 (/ISM) X2JCQ1 (/ISM) X2JGF9 (/ISM)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Receptor recycling GO:0001881
The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal.
9 M9NE66 (/IGI) M9NF56 (/IGI) M9NFQ1 (/IGI) Q9VSU8 (/IGI) X2J8V0 (/IGI) X2JAU8 (/IGI) X2JC77 (/IGI) X2JCQ1 (/IGI) X2JGF9 (/IGI)
Neuromuscular synaptic transmission GO:0007274
The process of communication from a neuron to a muscle, across a synapse.
9 M9NE66 (/IMP) M9NF56 (/IMP) M9NFQ1 (/IMP) Q9VSU8 (/IMP) X2J8V0 (/IMP) X2JAU8 (/IMP) X2JC77 (/IMP) X2JCQ1 (/IMP) X2JGF9 (/IMP)
Regulation of synaptic growth at neuromuscular junction GO:0008582
Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.
9 M9NE66 (/IMP) M9NF56 (/IMP) M9NFQ1 (/IMP) Q9VSU8 (/IMP) X2J8V0 (/IMP) X2JAU8 (/IMP) X2JC77 (/IMP) X2JCQ1 (/IMP) X2JGF9 (/IMP)
Regulation of Wnt signaling pathway GO:0030111
Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway.
9 M9NE66 (/IMP) M9NF56 (/IMP) M9NFQ1 (/IMP) Q9VSU8 (/IMP) X2J8V0 (/IMP) X2JAU8 (/IMP) X2JC77 (/IMP) X2JCQ1 (/IMP) X2JGF9 (/IMP)
Regulation of BMP signaling pathway GO:0030510
Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway.
9 M9NE66 (/IMP) M9NF56 (/IMP) M9NFQ1 (/IMP) Q9VSU8 (/IMP) X2J8V0 (/IMP) X2JAU8 (/IMP) X2JC77 (/IMP) X2JCQ1 (/IMP) X2JGF9 (/IMP)
Regulation of actin filament polymerization GO:0030833
Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.
9 M9NE66 (/IDA) M9NF56 (/IDA) M9NFQ1 (/IDA) Q9VSU8 (/IDA) X2J8V0 (/IDA) X2JAU8 (/IDA) X2JC77 (/IDA) X2JCQ1 (/IDA) X2JGF9 (/IDA)
Negative regulation of synaptic growth at neuromuscular junction GO:0045886
Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic growth at neuromuscular junction.
9 M9NE66 (/IGI) M9NF56 (/IGI) M9NFQ1 (/IGI) Q9VSU8 (/IGI) X2J8V0 (/IGI) X2JAU8 (/IGI) X2JC77 (/IGI) X2JCQ1 (/IGI) X2JGF9 (/IGI)
Negative regulation of synaptic growth at neuromuscular junction GO:0045886
Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic growth at neuromuscular junction.
9 M9NE66 (/IMP) M9NF56 (/IMP) M9NFQ1 (/IMP) Q9VSU8 (/IMP) X2J8V0 (/IMP) X2JAU8 (/IMP) X2JC77 (/IMP) X2JCQ1 (/IMP) X2JGF9 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 M9NE66 (/IDA) M9NF56 (/IDA) M9NFQ1 (/IDA) Q9VSU8 (/IDA) X2J8V0 (/IDA) X2JAU8 (/IDA) X2JC77 (/IDA) X2JCQ1 (/IDA) X2JGF9 (/IDA)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
9 M9NE66 (/IDA) M9NF56 (/IDA) M9NFQ1 (/IDA) Q9VSU8 (/IDA) X2J8V0 (/IDA) X2JAU8 (/IDA) X2JC77 (/IDA) X2JCQ1 (/IDA) X2JGF9 (/IDA)
Recycling endosome GO:0055037
An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.
9 M9NE66 (/IDA) M9NF56 (/IDA) M9NFQ1 (/IDA) Q9VSU8 (/IDA) X2J8V0 (/IDA) X2JAU8 (/IDA) X2JC77 (/IDA) X2JCQ1 (/IDA) X2JGF9 (/IDA)