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CATH Superfamily 2.170.270.10

SET domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
SET domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5100: Putative histone-lysine n-methyltransferase ehmt2

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Histone-lysine N-methyltransferase. [EC: 2.1.1.43]
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
    		 243 A0A024RCN9 A0A060WP13 A0A060X9P0 A0A061HZB3 A0A061IJI4 A0A061IM00 A0A087RE54 A0A087YGC0 A0A091CWT2 A0A091D5X8
    (233 more...)
    Non-specific serine/threonine protein kinase. [EC: 2.7.11.1]
    ATP + a protein = ADP + a phosphoprotein.
    • This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.
    • Formerly EC 2.7.1.37 and EC 2.7.1.70.
    		 2 A0A093V525 A0A0K8LLJ2
    Phospholipase A(2). [EC: 3.1.1.4]
    Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
    • Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.
    		 1 E0VU86