The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Hexapeptide repeat proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 81627: Probable UTP--glucose-1-phosphate uridylyltransfer...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
UTP:glucose-1-phosphate uridylyltransferase activity GO:0003983
Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.
4 A0A0G2K542 (/IDA) P08800 (/IDA) Q4V8I9 (/IDA) Q54YZ0 (/IDA)
UTP:glucose-1-phosphate uridylyltransferase activity GO:0003983
Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.
4 A5XCL5 (/ISS) E1JI91 (/ISS) Q9VSW1 (/ISS) Q9VSW2 (/ISS)
UTP:glucose-1-phosphate uridylyltransferase activity GO:0003983
Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.
3 P08800 (/IMP) P32861 (/IMP) P78811 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P32861 (/IPI) Q16851 (/IPI)
Glucose binding GO:0005536
Interacting selectively and non-covalently with the D- or L-enantiomer of glucose.
2 A0A0G2K542 (/IDA) Q4V8I9 (/IDA)
Pyrimidine ribonucleotide binding GO:0032557
Interacting selectively and non-covalently with a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
2 A0A0G2K542 (/IDA) Q4V8I9 (/IDA)
UTP:glucose-1-phosphate uridylyltransferase activity GO:0003983
Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.
1 Q16851 (/EXP)
UTP:glucose-1-phosphate uridylyltransferase activity GO:0003983
Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.
1 Q59KI0 (/IGI)
UTP:glucose-1-phosphate uridylyltransferase activity GO:0003983
Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.
1 Q91ZJ5 (/ISO)
UTP:glucose-1-phosphate uridylyltransferase activity GO:0003983
Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.
1 C8VK50 (/RCA)
UTP:glucose-1-phosphate uridylyltransferase activity GO:0003983
Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.
1 Q16851 (/TAS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q16851 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q91ZJ5 (/ISO)
Uridylyltransferase activity GO:0070569
Catalysis of the transfer of an uridylyl group to an acceptor.
1 P32861 (/IDA)

There are 28 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
UDP-glucose metabolic process GO:0006011
The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
4 A5XCL5 (/ISS) E1JI91 (/ISS) Q9VSW1 (/ISS) Q9VSW2 (/ISS)
Response to hyperoxia GO:0055093
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
4 A5XCL5 (/IMP) E1JI91 (/IMP) Q9VSW1 (/IMP) Q9VSW2 (/IMP)
Glycogen biosynthetic process GO:0005978
The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
2 P32861 (/IGI) Q59KI0 (/IGI)
Trehalose biosynthetic process GO:0005992
The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
2 P32861 (/IGI) Q59KI0 (/IGI)
UDP-glucose metabolic process GO:0006011
The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
2 A0A0G2K542 (/IDA) Q4V8I9 (/IDA)
UDP-glucose metabolic process GO:0006011
The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
2 P32861 (/IGI) Q59KI0 (/IGI)
UDP-glucose metabolic process GO:0006011
The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
2 P32861 (/IMP) P78811 (/IMP)
Pollen development GO:0009555
The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
2 P57751 (/IGI) Q9M9P3 (/IGI)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 P57751 (/IEP) Q9M9P3 (/IEP)
Glucose 1-phosphate metabolic process GO:0019255
The chemical reactions and pathways involving glucose 1-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-1.
2 A0A0G2K542 (/IDA) Q4V8I9 (/IDA)
Culmination involved in sorocarp development GO:0031154
The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.
2 P08800 (/IMP) Q54YZ0 (/IMP)
Callose deposition in cell wall GO:0052543
Any process in which callose is transported to, and/or maintained in, the cell wall. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
2 P57751 (/IGI) Q9M9P3 (/IGI)
Autophagosome assembly GO:0000045
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
1 Q54YZ0 (/IMP)
Glycogen metabolic process GO:0005977
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
1 Q54YZ0 (/IMP)
Glycogen biosynthetic process GO:0005978
The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
1 P32861 (/IMP)
Glycogen biosynthetic process GO:0005978
The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
1 Q16851 (/TAS)
Sucrose metabolic process GO:0005985
The chemical reactions and pathways involving sucrose, the disaccharide fructofuranosyl-glucopyranoside.
1 Q9M9P3 (/TAS)
UDP-glucose metabolic process GO:0006011
The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
1 O59819 (/ISO)
UDP-glucose metabolic process GO:0006011
The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
1 Q16851 (/TAS)
Galactose metabolic process GO:0006012
The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
1 C8VK50 (/RCA)
UDP-glucuronate biosynthetic process GO:0006065
The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.
1 Q16851 (/TAS)
(1->6)-beta-D-glucan biosynthetic process GO:0006078
The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.
1 Q59KI0 (/IGI)
(1->6)-beta-D-glucan biosynthetic process GO:0006078
The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.
1 P32861 (/IMP)
Protein glycosylation GO:0006486
A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
1 Q59KI0 (/IGI)
Positive regulation of cell death GO:0010942
Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
1 P57751 (/IMP)
Cellular response to phosphate starvation GO:0016036
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
1 Q9M9P3 (/IEP)
Cellulose biosynthetic process GO:0030244
The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.
1 Q54YZ0 (/IMP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 P57751 (/IEP)

There are 19 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 A5XCL5 (/IDA) E1JI91 (/IDA) O59819 (/IDA) P57751 (/IDA) P78811 (/IDA) Q9M9P3 (/IDA) Q9VSW1 (/IDA) Q9VSW2 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
6 Q69Z13 (/IDA) Q86D12 (/IDA) Q8WQE5 (/IDA) Q9XUS4 (/IDA) Q9XUS5 (/IDA) Q9XUS6 (/IDA)
Sarcomere GO:0030017
The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
6 Q69Z13 (/IDA) Q86D12 (/IDA) Q8WQE5 (/IDA) Q9XUS4 (/IDA) Q9XUS5 (/IDA) Q9XUS6 (/IDA)
Striated muscle dense body GO:0055120
A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.
6 Q69Z13 (/IDA) Q86D12 (/IDA) Q8WQE5 (/IDA) Q9XUS4 (/IDA) Q9XUS5 (/IDA) Q9XUS6 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 O59819 (/IDA) P78811 (/IDA) Q16851 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 A0A0G2K542 (/IDA) Q4V8I9 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P57751 (/IDA) Q9M9P3 (/IDA)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
1 Q4WAM5 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q91ZJ5 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q59KI0 (/IGI)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O59819 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q16851 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q59KI0 (/IGI)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q59KI0 (/IDA)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
1 P32861 (/IDA)
Yeast-form cell wall GO:0030445
The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form.
1 Q59KI0 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q16851 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q91ZJ5 (/ISO)
Pollen tube GO:0090406
A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain.
1 Q9M9P3 (/IDA)