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CATH Superfamily 2.160.10.10

Hexapeptide repeat proteins

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Hexapeptide repeat proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 81627: Probable UTP--glucose-1-phosphate uridylyltransfer...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
UTP--glucose-1-phosphate uridylyltransferase. [EC: 2.7.7.9]
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.
    		 254 A0A060T9H7 A0A060T9H7 A0A068JBU5 A0A068JBU5 A0A075B4T3 A0A075B4T3 A0A075E2Q1 A0A075E2Q1 A0A084GAV0 A0A084GAV0
    (244 more...)
    UTP-monosaccharide-1-phosphate uridylyltransferase. [EC: 2.7.7.64]
    UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide.
    • The reaction can occur in either direction and it has been postulated that MgUTP and Mg-diphosphate are the actual substrates.
    • Catalyzes the formation of UDP-Glc, UDP-Gal, UDP-GlcA, UDP-L-Ara and UDP-Xyl, showing broad substrate specificity toward monosaccharide 1-phosphates.
    • Mannose 1-phosphate, L-fucose 1-phosphate and glucose 6-phosphate are not substrates and UTP cannot be replaced by other nucleotide triphosphates.
    		 2 A0A170XLE0 A0A170XLE0