The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Cystine-knot cytokines
".
FunFam 2816: Gonadotropin subunit beta-2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Follicle-stimulating hormone receptor binding GO:0031762
Interacting selectively and non-covalently with a follicle-stimulating hormone receptor.
|
12 |
A0A068JIR5 (/ISS)
P01235 (/ISS)
P30984 (/ISS)
P53543 (/ISS)
Q14DX4 (/ISS)
Q306L6 (/ISS)
Q49L22 (/ISS)
Q9W6Q7 (/ISS)
T1PYH1 (/ISS)
V5QSM4 (/ISS)
(2 more) |
|
Lutropin-choriogonadotropic hormone receptor binding GO:0031775
Interacting selectively and non-covalently with a lutropin-choriogonadotropic hormone receptor.
|
12 |
A0A068JIR5 (/ISS)
P01235 (/ISS)
P30984 (/ISS)
P53543 (/ISS)
Q14DX4 (/ISS)
Q306L6 (/ISS)
Q49L22 (/ISS)
Q9W6Q7 (/ISS)
T1PYH1 (/ISS)
V5QSM4 (/ISS)
(2 more) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
12 |
A0A068JIR5 (/ISS)
P01235 (/ISS)
P30984 (/ISS)
P53543 (/ISS)
Q14DX4 (/ISS)
Q306L6 (/ISS)
Q49L22 (/ISS)
Q9W6Q7 (/ISS)
T1PYH1 (/ISS)
V5QSM4 (/ISS)
(2 more) |
|
Hormone activity GO:0005179
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
|
3 | P07732 (/IMP) Q800P3 (/IMP) Q9DG92 (/IMP) |
|
Hormone activity GO:0005179
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
|
2 | Q6QMF9 (/IDA) Q6TCF5 (/IDA) |
|
Follicle-stimulating hormone receptor binding GO:0031762
Interacting selectively and non-covalently with a follicle-stimulating hormone receptor.
|
2 | Q9DG80 (/IDA) W5UK74 (/IDA) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | Q9DG80 (/IPI) W5UK74 (/IPI) |
|
Lutropin-choriogonadotropic hormone receptor binding GO:0031775
Interacting selectively and non-covalently with a lutropin-choriogonadotropic hormone receptor.
|
1 | Q9DG80 (/IDA) |
There are 22 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
12 |
A0A068JIR5 (/ISS)
P01235 (/ISS)
P30984 (/ISS)
P53543 (/ISS)
Q14DX4 (/ISS)
Q306L6 (/ISS)
Q49L22 (/ISS)
Q9W6Q7 (/ISS)
T1PYH1 (/ISS)
V5QSM4 (/ISS)
(2 more) |
|
Positive regulation of androgen secretion GO:2000836
Any process that activates or increases the frequency, rate or extent of androgen secretion.
|
12 |
A0A068JIR5 (/ISS)
P01235 (/ISS)
P30984 (/ISS)
P53543 (/ISS)
Q14DX4 (/ISS)
Q306L6 (/ISS)
Q49L22 (/ISS)
Q9W6Q7 (/ISS)
T1PYH1 (/ISS)
V5QSM4 (/ISS)
(2 more) |
|
Positive regulation of estradiol secretion GO:2000866
Any process that activates or increases the frequency, rate or extent of estradiol secretion.
|
12 |
A0A068JIR5 (/ISS)
P01235 (/ISS)
P30984 (/ISS)
P53543 (/ISS)
Q14DX4 (/ISS)
Q306L6 (/ISS)
Q49L22 (/ISS)
Q9W6Q7 (/ISS)
T1PYH1 (/ISS)
V5QSM4 (/ISS)
(2 more) |
|
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
|
3 | C0HA57 (/IDA) Q9DG92 (/IDA) Q9W6Q7 (/IDA) |
|
Oocyte maturation GO:0001556
A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.
|
2 | Q6QMF9 (/IMP) Q6TCF5 (/IMP) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
2 | Q6QMF9 (/IGI) Q6TCF5 (/IGI) |
|
Sex determination GO:0007530
Any process that establishes and transmits the specification of sexual status of an individual organism.
|
2 | Q6QMF9 (/IGI) Q6TCF5 (/IGI) |
|
Female gonad development GO:0008585
The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.
|
2 | Q6QMF9 (/IGI) Q6TCF5 (/IGI) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | Q9DG80 (/IDA) W5UK74 (/IDA) |
|
Ovulation GO:0030728
The release of a mature ovum/oocyte from an ovary.
|
2 | Q6QMF9 (/IMP) Q6TCF5 (/IMP) |
|
Response to steroid hormone GO:0048545
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
|
2 | C0HA57 (/IDA) Q9W6Q7 (/IDA) |
|
Positive regulation of androgen secretion GO:2000836
Any process that activates or increases the frequency, rate or extent of androgen secretion.
|
2 | Q9DG80 (/IMP) W5UK74 (/IMP) |
|
Positive regulation of estradiol secretion GO:2000866
Any process that activates or increases the frequency, rate or extent of estradiol secretion.
|
2 | Q9DG80 (/IDA) W5UK74 (/IDA) |
|
Androgen biosynthetic process GO:0006702
The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
|
1 | Q9DG92 (/IDA) |
|
Gene expression GO:0010467
The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q9DG92 (/IDA) |
|
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
|
1 | Q9DG92 (/IDA) |
|
Testosterone secretion GO:0035936
The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.
|
1 | P07732 (/IMP) |
|
Estradiol secretion GO:0035938
The regulated release of estradiol into the circulatory system.
|
1 | A5JSW4 (/IMP) |
|
Androstenedione secretion GO:0035941
The regulated release of androstenedione (androst-4-ene-3,17-dione) into the circulatory system.
|
1 | P07732 (/IMP) |
|
Progesterone secretion GO:0042701
The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta.
|
1 | P07732 (/IMP) |
|
Testosterone biosynthetic process GO:0061370
The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.
|
1 | P07732 (/IMP) |
|
Response to aromatase inhibitor GO:0061477
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus.
|
1 | Q9W6Q7 (/IDA) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q9DG92 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P07732 (/IMP) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q9DG92 (/TAS) |
