The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Complement Module, domain 1
".
FunFam 17155: Alpha-1 type III collagen
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protease binding GO:0002020
Interacting selectively and non-covalently with any protease or peptidase.
|
1 | P02461 (/IPI) |
Protease binding GO:0002020
Interacting selectively and non-covalently with any protease or peptidase.
|
1 | P08121 (/ISO) |
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
1 | P02461 (/IMP) |
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
1 | P08121 (/ISO) |
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
1 | P02461 (/NAS) |
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
|
1 | P02461 (/IMP) |
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
|
1 | P08121 (/ISO) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P02461 (/IPI) |
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
|
1 | P08121 (/IPI) |
Platelet-derived growth factor binding GO:0048407
Interacting selectively and non-covalently with platelet-derived growth factor.
|
1 | P02461 (/IDA) |
Platelet-derived growth factor binding GO:0048407
Interacting selectively and non-covalently with platelet-derived growth factor.
|
1 | P08121 (/ISO) |
There are 48 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Regulation of ossification GO:0030278
Any process that modulates the frequency, rate or extent of bone formation.
|
4 | B1WB89 (/IMP) F1QJC9 (/IMP) F1QSC5 (/IMP) Q6U1J5 (/IMP) |
Fin regeneration GO:0031101
The regrowth of fin tissue following its loss or destruction.
|
4 | B1WB89 (/IMP) F1QJC9 (/IMP) F1QSC5 (/IMP) Q6U1J5 (/IMP) |
Fin development GO:0033333
The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.
|
4 | B1WB89 (/IMP) F1QJC9 (/IMP) F1QSC5 (/IMP) Q6U1J5 (/IMP) |
Fin morphogenesis GO:0033334
The process in which the anatomical structures of a fin are generated and organized.
|
4 | B1WB89 (/IMP) F1QJC9 (/IMP) F1QSC5 (/IMP) Q6U1J5 (/IMP) |
Pectoral fin development GO:0033339
The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.
|
4 | B1WB89 (/IMP) F1QJC9 (/IMP) F1QSC5 (/IMP) Q6U1J5 (/IMP) |
Cerebral cortex development GO:0021987
The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.
|
2 | P02461 (/ISS) P13941 (/ISS) |
Collagen fibril organization GO:0030199
Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.
|
2 | P02461 (/IMP) P08121 (/IMP) |
Positive regulation of Rho protein signal transduction GO:0035025
Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction.
|
2 | P02461 (/ISS) P13941 (/ISS) |
Negative regulation of neuron migration GO:2001223
Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration.
|
2 | P02461 (/ISS) P13941 (/ISS) |
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
|
1 | P13941 (/IEP) |
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
|
1 | P08121 (/IMP) |
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
|
1 | P02461 (/IDA) |
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
|
1 | P08121 (/ISO) |
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P02461 (/IDA) |
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P08121 (/ISO) |
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P02461 (/IMP) |
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P08121 (/ISO) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | P02461 (/IMP) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | P08121 (/ISO) |
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
|
1 | P13941 (/IEP) |
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
|
1 | P02461 (/IDA) |
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
|
1 | P08121 (/ISO) |
Response to mechanical stimulus GO:0009612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
|
1 | P13941 (/IEP) |
Peptide cross-linking GO:0018149
The formation of a covalent cross-link between or within protein chains.
|
1 | P02461 (/IDA) |
Peptide cross-linking GO:0018149
The formation of a covalent cross-link between or within protein chains.
|
1 | P08121 (/ISO) |
Cerebral cortex development GO:0021987
The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.
|
1 | P08121 (/IMP) |
Platelet activation GO:0030168
A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
|
1 | P02461 (/NAS) |
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
|
1 | P02461 (/TAS) |
Collagen fibril organization GO:0030199
Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.
|
1 | P08121 (/ISO) |
Collagen fibril organization GO:0030199
Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.
|
1 | P02461 (/NAS) |
Collagen catabolic process GO:0030574
The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.
|
1 | P02461 (/TAS) |
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
|
1 | P02461 (/IDA) |
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
|
1 | P08121 (/ISO) |
Positive regulation of Rho protein signal transduction GO:0035025
Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction.
|
1 | P08121 (/IDA) |
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
|
1 | P02461 (/IDA) |
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
|
1 | P08121 (/ISO) |
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
|
1 | P02461 (/NAS) |
Skin development GO:0043588
The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
|
1 | P02461 (/IMP) |
Skin development GO:0043588
The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
|
1 | P08121 (/ISO) |
Digestive tract development GO:0048565
The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.
|
1 | P08121 (/IMP) |
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
1 | P02461 (/TAS) |
Negative regulation of immune response GO:0050777
Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
1 | P02461 (/IMP) |
Negative regulation of immune response GO:0050777
Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
1 | P08121 (/ISO) |
Aorta smooth muscle tissue morphogenesis GO:0060414
The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.
|
1 | P08121 (/IMP) |
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
|
1 | P08121 (/IDA) |
Supramolecular fiber organization GO:0097435
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.
|
1 | P02461 (/IMP) |
Supramolecular fiber organization GO:0097435
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.
|
1 | P08121 (/ISO) |
Negative regulation of neuron migration GO:2001223
Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration.
|
1 | P08121 (/IMP) |
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | B1WB89 (/IDA) F1QJC9 (/IDA) F1QSC5 (/IDA) Q6U1J5 (/IDA) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | P02461 (/TAS) P12105 (/TAS) |
Collagen type III trimer GO:0005586
A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils.
|
2 | P02461 (/IDA) P08121 (/IDA) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P02461 (/IDA) P08121 (/IDA) |
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support for cells or tissues.
|
2 | P08121 (/IDA) P13941 (/IDA) |
Proteinaceous extracellular matrix GO:0005578
A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus.
|
1 | P08121 (/IDA) |
Collagen trimer GO:0005581
A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures.
|
1 | P08121 (/IDA) |
Collagen type III trimer GO:0005586
A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils.
|
1 | P02461 (/IMP) |
Collagen type III trimer GO:0005586
A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils.
|
1 | P08121 (/ISO) |
Collagen type III trimer GO:0005586
A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils.
|
1 | P02461 (/NAS) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P08121 (/ISO) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P02461 (/NAS) |
Endoplasmic reticulum lumen GO:0005788
The volume enclosed by the membranes of the endoplasmic reticulum.
|
1 | P02461 (/TAS) |
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support for cells or tissues.
|
1 | P02461 (/IMP) |
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support for cells or tissues.
|
1 | P08121 (/ISO) |