The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Complement Module, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
17461
4608
3D
1e88A03 - 59.2
17214
4419
EC
3D
2ehfA00 - 99.2
17206
3485
3D
1h03P02 - 95.1
17205
2649
3D
4c16A03 - 95.4
17136
2172 - - 95.8
17427
1342 - - 96.9
17110
1253 - - 97.2
17050
1079 - - 88.8
17185
1021 - - 90.9
16907
996 - - 95.0
17124
813 - - 89.6
17220
696
3D
1hccA00 - 96.9
17406
660
EC
3D
1gpzA04 - 96.1
17400
600 - - 93.6
17439
597 - - 85.7
17380
572 - - 95.8
16780
510 - - 77.4
17422
493 - - 89.7
17385
471 - - 96.6
16783
420 - - 93.3
17419
404 - - 94.4
17137
399 - - 90.7
17142
374
3D
4b2rA01 - 92.6
17156
368
3D
3sw0X01 - 93.5
16750
363 - - 68.8
16802
358 - - 80.1
16803
350 - - 94.8
17150
337 - - 88.7
17233
327
3D
2uwnA01 - 92.1
16857
315 - - 85.0
17377
282 - - 86.6
16816
266 - - 80.7
17113
264 - - 94.6
17415
258 - - 96.2
16877
247
3D
4k12A00 - 95.4
17148
240
3D
2ybyA02 - 90.1
17155
223 - - 68.7
16898
198 - - 95.1
15350
197 - - 18.6
17135
II
186
3D
1u5mA01 - 76.9
2709
175 - - 54.1
17473
157 - - 92.4
16924
157
EC
3D
3erbA03 - 80.8
17035
156 - - 58.2
16903
154
3D
2a55A02 - 82.9
6225
154 - - 55.2
3072
146
3D
2yraA00 - 48.4
1767
145 - - 57.0
17212
140
EC
- - 89.7
14478
137 - - 25.0
1765
136 - - 29.1
17128
136 - - 81.8
16638
133
3D
2rlpA01 - 79.6
17160
132 - - 51.9
12304
132 - - 85.4
1751
129 - - 63.1
16845
126
3D
2xrbA04 - 71.8
13646
126 - - 36.6
17194
123 - - 67.4
15352
122 - - 45.6
7417
122 - - 39.9
17000
120 - - 54.9
16380
119
3D
3govA01 - 59.9
16871
118
EC
- - 86.4
17151
118
3D
1cklA01 - 94.6
16386
118 - - 47.0
16438
117 - - 54.4
16479
115 - - 29.1
16961
114
EC
- - 64.6
15241
113 - - 53.3
5072
110 - - 58.8
16459
110 - - 71.9
17247
106
3D
2a55A01 - 86.8
16934
105 - - 64.5
16614
104 - - 74.9
16778
104
EC
3D
3erbA01 - 72.1
16888
102 - - 95.1
16471
101 - - 73.9
16482
99
3D
1c1zA05 - 79.7
16894
98
3D
2bzmA02 - 91.8
16537
98
EC
3D
3erbA02 - 61.5
16554
95
3D
1c1zA04 - 60.2
16389
95 - - 57.5
16956
94
3D
1nwvA01 - 75.5
16899
94 - - 80.2
16896
91
3D
4c16A04 - 78.1
16508
90
EC
3D
2xwbF01 - 62.3
16402
90 - - 51.3
14941
90 - - 40.9
12637
89 - - 77.1
16827
89
3D
1gknA01 - 73.9
16624
88
EC
3D
4losA02 - 82.5
17146
88 - - 50.4
16955
87 - - 55.2
16763
86 - - 49.1
12450
86 - - 42.0
16463
83 - - 50.6
16407
83 - - 53.4
17070
82 - - 81.9
17152
81 - - 89.8
1336
80 - - 55.1
16426
80 - - 66.2
17003
80 - - 69.2
16450
78 - - 42.5
16921
77 - - 35.4
3886
77 - - 52.4
16782
77
EC
3D
1tpgA01 - 67.7
16548
77 - - 68.5
7623
75 - - 44.6
16796
75 - - 77.7
16929
74
3D
1cklA02 - 72.8
16937
74 - - 24.3
4942
73 - - 6.5
1054
Predicted
73
EC
- - 40.9
3419
72 - - 22.3
2736
71 - - 46.0
17019
71 - - 91.6
16983
71 - - 44.1
17203
70
3D
2wiiC04 - 79.1
3420
70 - - 19.7
16378
69
EC
3D
2qy0A01 - 66.6
16488
68 - - 45.8
16772
68 - - 68.9
17047
67 - - 37.6
4500
67 - - 17.8
4299
66 - - 25.6
16728
66
3D
1c1zA02 - 52.5
17004
66 - - 9.2
6244
66 - - 32.8
1408
65
3D
1srzA00 - 29.6
7421
65 - - 39.6
16922
64 - - 76.6
16689
64 - - 41.7
16458
64
3D
3sw0X02 - 46.2
16489
64 - - 58.5
17431
63 - - 91.4
16764
62 - - 79.0
2781
62
3D
1e5gA01 - 19.8
16788
62
3D
3t5oA04 - 74.8
16847
62
3D
4b2rA02 - 68.7
16446
61 - - 42.5
16642
61 - - 53.5
2428
61 - - 36.9
2138
Predicted
61
EC
- - 44.8
16440
59
3D
2jgwA00 - 52.7
1275
59
3D
1g40A01 - 13.6
16499
59 - - 71.8
16523
59
3D
1c1zA03 - 63.9
16542
58
3D
1c1zA01 - 61.3
3150
57
3D
1ojvA01 - 54.3
2187
55 - - 30.6
16784
55 - - 58.4
16990
54 - - 72.8
16381
Predicted
53
EC
- - 53.4
1764
53
EC
- - 28.3
16982
53 - - 40.8
16553
51 - - 58.5
16500
51 - - 55.2
16539
49 - - 70.8
16455
48
3D
1gkgA01 - 31.6
16423
48 - - 34.2
16461
47 - - 12.8
16613
46 - - 50.2
17347
46 - - 65.6
16388
46 - - 40.9
9196
45 - - 14.6
16838
45 - - 72.0
16393
44
EC
3D
1zjkA01 - 57.0
16545
44 - - 49.1
16432
42 - - 39.3
16541
42
3D
1h03P01 - 23.5
3100
39 - - 18.1
5654
39 - - 41.8
16609
38
3D
4wjg201 - 48.1
1588
37 - - 42.9
1263
35 - - 32.8
16774
35 - - 67.0
17320
35 - - 64.5
10301
33 - - 31.3
16563
33 - - 45.3
16514
32 - - 57.5
16761
32
3D
2rlqA01 - 55.3
16746
32 - - 58.8
17052
31 - - 81.2
2710
30
3D
3zd2A01 - 31.0
16572
30 - - 66.9
3421
29 - - 19.7
16742
29
3D
2rlqA02 - 55.3
2685
28 - - 28.7
11889
28 - - 40.3
16731
27
3D
3t5oA03 - 61.4
16561
27 - - 49.5
16448
26 - - 48.2
13651
26 - - 16.5
11048
26 - - 49.5
9677
25 - - 34.6
14062
I
25 - - 14.0
9913
24 - - 63.3
361
24 - - 47.3
3602
23 - - 10.5
16566
23 - - 35.2
16521
22 - - 55.0
7437
21
3D
1hfhA01 - 19.9
1933
21 - - 24.2
16932
21 - - 67.8
16734
21 - - 46.8
4687
19 - - 26.7
16456
19 - - 35.5
17127
19 - - 77.8
2705
18
3D
2mcyA01 - 26.5
4491
18 - - 21.6
9716
18 - - 22.1
6666
18 - - 23.2
16398
16
3D
2mczA01 - 28.0
1056
15 - - 23.0
811
15 - - 34.2
6238
15 - - 23.8
9628
14 - - 17.3
5196
14 - - 24.5
3483
14 - - 24.7
7420
14 - - 8.1
2038
14 - - 17.4
4174
13 - - 12.7
10095
13 - - 27.5
2797
13 - - 6.0
17097
13 - - 62.3
12396
13 - - 5.6
9569
13 - - 29.7
2578
13
3D
1ghqB01 - 18.5
5609
12 - - 11.0
1758
12 - - 0.0
3807
12 - - 39.0
3415
11 - - 5.9
645
11 - - 12.8
5195
11 - - 16.7
9648
11 - - 5.9
6230
11 - - 17.4
8016
11 - - 17.3
2918
10 - - 12.6
2148
10
3D
2uwnA03 - 9.6
3443
10 - - 12.8
1445
9 - - 13.0
5085
9 - - 9.2
12140
9 - - 0.0
3512
9 - - 3.5
5074
9 - - 26.4
16534
8 - - 20.2
13650
8 - - 3.4
8644
8 - - 13.0
4338
7 - - 19.5
8404
7 - - 8.9
13638
7 - - 0.0
2147
7 - - 2.7
5686
7 - - 4.0
17088
7 - - 0.0
14077
7 - - 3.5
12251
7 - - 4.1
75
7 - - 10.5
14170
6 - - 6.9
7192
6 - - 8.2
4172
6 - - 2.0
2249
6 - - 12.6
7540
6 - - 0.0
10489
6 - - 20.9
9159
6 - - 9.1
13643
6 - - 28.2
6216
5 - - 10.6
14944
5 - - 6.3
13470
5 - - 10.0
5105
5 - - 10.7
14475
5 - - 9.5
7852
5 - - 3.6
12981
5 - - 7.4
2140
5 - - 0.0
2714
5 - - 1.9
14066
5 - - 3.5
15894
5
EC
- - 3.6
1235
5 - - 11.0
7428
5 - - 0.0
8790
5 - - 6.5
9748
4 - - 10.1
16970
4 - - 0.0
4184
4 - - 1.9
11838
4 - - 28.8
14947
4 - - 10.9
15378
4 - - 0.0
14065
4 - - 0.0
17234
4 - - 0.0
14474
4 - - 3.5
9644
4 - - 12.1
4194
4 - - 0.0
13640
4 - - 10.3
2892
4 - - 4.1
1158
4 - - 3.8
6433
4 - - 14.8
16588
4 - - 21.0
9749
4 - - 2.1
5104
3 - - 4.0
4208
3 - - 0.0
13633
3 - - 0.0
9651
3 - - 0.0
1760
3
EC
- - 4.9
8072
3 - - 12.1
5066
3
EC
- - 13.5
14068
3 - - 12.6
14055
I
3 - - 10.6
8073
3 - - 7.7
16574
3 - - 13.9
981
3 - - 27.8
9642
3 - - 14.5
1769
3 - - 0.0
6618
3 - - 2.2
6243
2 - - 14.7
512
2 - - 0.0
6233
2 - - 0.0
5357
GABA GABBR1
2 - - 0.0
9639
2 - - 14.0
4445
2 - - 0.0
3417
2 - - 0.0
14946
2 - - 7.1
5587
2 - - 0.0
2142
2 - - 0.0
4446
2 - - 0.0
1770
2 - - 0.0
12949
2 - - 0.0
4385
2 - - 3.5
12049
2 - - 19.4
4575
2 - - 3.5
12441
2 - - 0.0
5589
2 - - 0.0
3479
2 - - 0.0
5100
2 - - 0.0
812
2 - - 0.0
8630
2 - - 0.0
16658
2
EC
- - 17.6
647
2
EC
- - 1.7
3434
2
EC
- - 1.8
5588
2 - - 0.0
5411
2 - - 5.9
6241
2 - - 2.0
3409
2 - - 0.0
13396
2 - - 0.0
3734
2 - - 0.0
2720
2 - - 0.0
3577
2 - - 0.0
12153
1 - - 0.0
2743
1 - - 0.0
51
1 - - 0.0
14859
1 - - 0.0
11405
1 - - 0.0
11826
1 - - 0.0
16317
1 - - 0.0
5056
1 - - 0.0
649
1 - - 0.0
8966
1 - - 0.0
16673
1 - - 0.0
15019
1 - - 0.0
16314
1 - - 0.0
7446
1 - - 0.0