The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Complement Module, domain 1
".
FunFam 16542: Beta-2-glycoprotein 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Glycoprotein binding GO:0001948
Interacting selectively and non-covalently with a glycoprotein, a protein that contains covalently bound glycose (monosaccharide) residues. These also include proteoglycans.
|
1 | P02749 (/IPI) |
Glycoprotein binding GO:0001948
Interacting selectively and non-covalently with a glycoprotein, a protein that contains covalently bound glycose (monosaccharide) residues. These also include proteoglycans.
|
1 | Q01339 (/ISO) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P02749 (/IPI) |
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
1 | P02749 (/IDA) |
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
1 | Q01339 (/ISO) |
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
|
1 | P02749 (/IDA) |
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
|
1 | Q01339 (/ISO) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | P02749 (/IPI) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q01339 (/ISO) |
Lipoprotein lipase activator activity GO:0060230
Binds to and increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein.
|
1 | P02749 (/IDA) |
Lipoprotein lipase activator activity GO:0060230
Binds to and increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein.
|
1 | Q01339 (/ISO) |
There are 28 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Negative regulation of endothelial cell proliferation GO:0001937
Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
|
1 | P02749 (/IDA) |
Negative regulation of endothelial cell proliferation GO:0001937
Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
|
1 | Q01339 (/ISO) |
Platelet degranulation GO:0002576
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
|
1 | P02749 (/TAS) |
Triglyceride metabolic process GO:0006641
The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
|
1 | P02749 (/IDA) |
Triglyceride metabolic process GO:0006641
The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
|
1 | Q01339 (/ISO) |
Blood coagulation, intrinsic pathway GO:0007597
A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X.
|
1 | P02749 (/IDA) |
Blood coagulation, intrinsic pathway GO:0007597
A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X.
|
1 | Q01339 (/ISO) |
Negative regulation of endothelial cell migration GO:0010596
Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
1 | P02749 (/IDA) |
Negative regulation of endothelial cell migration GO:0010596
Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
1 | Q01339 (/ISO) |
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
|
1 | P02749 (/IDA) |
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
|
1 | Q01339 (/ISO) |
Regulation of blood coagulation GO:0030193
Any process that modulates the frequency, rate or extent of blood coagulation.
|
1 | Q01339 (/IMP) |
Positive regulation of blood coagulation GO:0030194
Any process that activates or increases the frequency, rate or extent of blood coagulation.
|
1 | P02749 (/TAS) |
Negative regulation of blood coagulation GO:0030195
Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
|
1 | P02749 (/IDA) |
Negative regulation of blood coagulation GO:0030195
Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
|
1 | Q01339 (/ISO) |
Plasminogen activation GO:0031639
The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.
|
1 | P02749 (/IDA) |
Plasminogen activation GO:0031639
The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.
|
1 | Q01339 (/ISO) |
Negative regulation of myeloid cell apoptotic process GO:0033033
Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process.
|
1 | P02749 (/IDA) |
Negative regulation of myeloid cell apoptotic process GO:0033033
Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process.
|
1 | Q01339 (/ISO) |
Triglyceride transport GO:0034197
The directed movement of triglyceride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
|
1 | P02749 (/ISS) |
Negative regulation of smooth muscle cell apoptotic process GO:0034392
Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process.
|
1 | P02749 (/IDA) |
Negative regulation of smooth muscle cell apoptotic process GO:0034392
Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process.
|
1 | Q01339 (/ISO) |
Positive regulation of lipoprotein lipase activity GO:0051006
Any process that activates or increases the activity of the enzyme lipoprotein lipase.
|
1 | P02749 (/IDA) |
Positive regulation of lipoprotein lipase activity GO:0051006
Any process that activates or increases the activity of the enzyme lipoprotein lipase.
|
1 | Q01339 (/ISO) |
Regulation of fibrinolysis GO:0051917
Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
|
1 | P02749 (/IDA) |
Regulation of fibrinolysis GO:0051917
Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
|
1 | Q01339 (/ISO) |
Negative regulation of fibrinolysis GO:0051918
Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
|
1 | P02749 (/IDA) |
Negative regulation of fibrinolysis GO:0051918
Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
|
1 | Q01339 (/ISO) |
There are 14 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P02749 (/IDA) Q01339 (/IDA) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | P02749 (/TAS) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q01339 (/ISO) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | P02749 (/IDA) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | Q01339 (/ISO) |
Platelet dense granule lumen GO:0031089
The volume enclosed by the membrane of the platelet dense granule.
|
1 | P02749 (/TAS) |
Very-low-density lipoprotein particle GO:0034361
A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver.
|
1 | P02749 (/IDA) |
Very-low-density lipoprotein particle GO:0034361
A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver.
|
1 | Q01339 (/ISO) |
High-density lipoprotein particle GO:0034364
A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.
|
1 | P02749 (/IDA) |
High-density lipoprotein particle GO:0034364
A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.
|
1 | Q01339 (/ISO) |
Chylomicron GO:0042627
A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.
|
1 | P02749 (/IDA) |
Chylomicron GO:0042627
A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.
|
1 | Q01339 (/ISO) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | P02749 (/IDA) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q01339 (/ISO) |