The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Mitochondrial carrier domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9458: Mitochondrial Carrier (MC) Family

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
S-adenosyl-L-methionine transmembrane transporter activity GO:0000095
Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
4 Q4V9P0 (/ISS) Q641C8 (/ISS) Q6GLA2 (/ISS) Q9VBN7 (/ISS)
S-adenosyl-L-methionine transmembrane transporter activity GO:0000095
Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
2 P38921 (/IDA) Q94AG6 (/IDA)
S-adenosyl-L-methionine transmembrane transporter activity GO:0000095
Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
1 P38921 (/IGI)
S-adenosyl-L-methionine transmembrane transporter activity GO:0000095
Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
1 P38921 (/IMP)
S-adenosyl-L-methionine transmembrane transporter activity GO:0000095
Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
1 Q10442 (/ISO)
Iron ion transmembrane transporter activity GO:0005381
Catalysis of the transfer of iron (Fe) ions from one side of a membrane to the other.
1 P10566 (/IMP)
Iron ion transmembrane transporter activity GO:0005381
Catalysis of the transfer of iron (Fe) ions from one side of a membrane to the other.
1 Q55DY8 (/ISS)
Ferrous iron transmembrane transporter activity GO:0015093
Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
1 P10566 (/EXP)
Glycine transmembrane transporter activity GO:0015187
Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid.
1 Q07534 (/IDA)
Glycine transmembrane transporter activity GO:0015187
Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid.
1 Q07534 (/IGI)
Glycine transmembrane transporter activity GO:0015187
Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid.
1 Q07534 (/IMP)
Glycine transmembrane transporter activity GO:0015187
Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid.
1 Q9P6N6 (/ISO)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
S-adenosyl-L-methionine transport GO:0015805
The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 Q4V9P0 (/ISS) Q641C8 (/ISS) Q6GLA2 (/ISS) Q9VBN7 (/ISS)
S-adenosyl-L-methionine transport GO:0015805
The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P38921 (/IDA) Q94AG6 (/IDA)
Heme biosynthetic process GO:0006783
The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
1 Q07534 (/IGI)
Heme biosynthetic process GO:0006783
The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
1 Q07534 (/IMP)
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
1 P10566 (/IGI)
Chloroplast organization GO:0009658
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast.
1 Q94AG6 (/IMP)
S-adenosyl-L-methionine transport GO:0015805
The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P38921 (/IGI)
S-adenosyl-L-methionine transport GO:0015805
The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P38921 (/IMP)
Hemoglobin metabolic process GO:0020027
The chemical reactions and pathways involving hemoglobin, including its uptake and utilization.
1 Q08CI8 (/IGI)
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
1 Q08CI8 (/IMP)
Hemoglobin biosynthetic process GO:0042541
The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
1 Q08CI8 (/IGI)
Small molecule metabolic process GO:0044281
The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
1 P10566 (/TAS)
Mitochondrial iron ion transport GO:0048250
The directed movement of iron ions into, out of or within a mitochondrion.
1 P10566 (/IDA)
Mitochondrial iron ion transport GO:0048250
The directed movement of iron ions into, out of or within a mitochondrion.
1 Q55DY8 (/ISS)
Iron ion homeostasis GO:0055072
Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell.
1 Q5A2T7 (/IMP)
Transmembrane glycine transport from cytosol to mitochondrion GO:1904983
The directed movement of glycine across a membrane from cytosol to mitochondrion.
1 Q9P6N6 (/IC)
Transmembrane glycine transport from cytosol to mitochondrion GO:1904983
The directed movement of glycine across a membrane from cytosol to mitochondrion.
1 Q07534 (/IGI)
Transmembrane glycine transport from cytosol to mitochondrion GO:1904983
The directed movement of glycine across a membrane from cytosol to mitochondrion.
1 Q07534 (/IMP)
Mitochondrial S-adenosyl-L-methionine transmembrane transport GO:1990543
The directed movement of S-adenosyl-L-methionine from one side of a membrane to the other into, out of or within a mitochondrion.
1 Q10442 (/ISS)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
7 P38921 (/ISS) Q07534 (/ISS) Q10442 (/ISS) Q4V9P0 (/ISS) Q641C8 (/ISS) Q6GLA2 (/ISS) Q9VBN7 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 P10566 (/IDA) P38921 (/IDA) Q07534 (/IDA) Q5A2T7 (/IDA) Q94AG6 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q55DY8 (/ISS)
Mitochondrial envelope GO:0005740
The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
1 Q9P6N6 (/NAS)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
1 P10566 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q5A2T7 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 Q94AG6 (/IDA)
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
1 Q94AG6 (/IDA)
Chloroplast envelope GO:0009941
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
1 Q94AG6 (/IDA)