The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6352: Protein farnesyltransferase subunit beta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
9 O13782 (/ISS) P22007 (/ISS) P49355 (/ISS) Q02293 (/ISS) Q04903 (/ISS) Q38920 (/ISS) Q55D51 (/ISS) Q8IHP6 (/ISS) Q8K2I1 (/ISS)
Protein farnesyltransferase activity GO:0004660
Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.
6 P49355 (/ISS) Q04903 (/ISS) Q38920 (/ISS) Q55D51 (/ISS) Q8IHP6 (/ISS) Q8K2I1 (/ISS)
Protein farnesyltransferase activity GO:0004660
Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.
4 O13782 (/IDA) P22007 (/IDA) P49356 (/IDA) Q02293 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 P22007 (/IPI) P49356 (/IPI) Q02293 (/IPI) Q38920 (/IPI)
Farnesyltranstransferase activity GO:0004311
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
1 Q8K2I1 (/IMP)
Farnesyltranstransferase activity GO:0004311
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
1 Q38920 (/ISS)
Protein farnesyltransferase activity GO:0004660
Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.
1 Q8K2I1 (/ISO)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 P49356 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 Q8K2I1 (/ISO)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein farnesylation GO:0018343
The covalent attachment of a farnesyl group to a protein.
7 P49355 (/ISS) Q02293 (/ISS) Q04903 (/ISS) Q38920 (/ISS) Q55D51 (/ISS) Q8IHP6 (/ISS) Q8K2I1 (/ISS)
Protein farnesylation GO:0018343
The covalent attachment of a farnesyl group to a protein.
3 O13782 (/IDA) P22007 (/IDA) P49356 (/IDA)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 Q02293 (/IMP) Q8K2I1 (/IMP)
Cardiac ventricle development GO:0003231
The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
1 Q6IQG3 (/IMP)
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q8K2I1 (/IMP)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
1 Q38920 (/IMP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
1 Q38920 (/IMP)
Negative regulation of abscisic acid-activated signaling pathway GO:0009788
Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.
1 Q38920 (/IMP)
Regulation of meristem structural organization GO:0009934
Any process that modulates the frequency, rate or extent of meristem organization.
1 Q38920 (/IMP)
Response to inorganic substance GO:0010035
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
1 Q02293 (/IMP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 Q02293 (/IMP)
Protein prenylation GO:0018342
The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.
1 Q38920 (/IMP)
Protein prenylation GO:0018342
The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.
1 A0A1D8PLY3 (/NAS)
Protein farnesylation GO:0018343
The covalent attachment of a farnesyl group to a protein.
1 Q8K2I1 (/ISO)
Regulation of rhodopsin mediated signaling pathway GO:0022400
Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling.
1 P49356 (/TAS)
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
1 Q02293 (/IMP)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
1 Q8K2I1 (/IMP)
Positive regulation of cell cycle GO:0045787
Any process that activates or increases the rate or extent of progression through the cell cycle.
1 Q02293 (/IMP)
Positive regulation of fibroblast proliferation GO:0048146
Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
1 Q8K2I1 (/IMP)
Positive regulation of nitric-oxide synthase biosynthetic process GO:0051770
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme.
1 Q02293 (/IMP)
Protein targeting to plasma membrane GO:0072661
The process of directing proteins towards the plasma membrane; usually uses signals contained within the protein.
1 O13782 (/IC)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein farnesyltransferase complex GO:0005965
A protein complex that possesses protein farnesyltransferase activity.
8 O13782 (/ISS) P49355 (/ISS) Q02293 (/ISS) Q04903 (/ISS) Q38920 (/ISS) Q55D51 (/ISS) Q8IHP6 (/ISS) Q8K2I1 (/ISS)
Protein farnesyltransferase complex GO:0005965
A protein complex that possesses protein farnesyltransferase activity.
2 P22007 (/IDA) P49356 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O13782 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O13782 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P49356 (/TAS)
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
1 P49356 (/IDA)
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
1 Q8K2I1 (/ISO)
Protein farnesyltransferase complex GO:0005965
A protein complex that possesses protein farnesyltransferase activity.
1 O13782 (/IPI)
Protein farnesyltransferase complex GO:0005965
A protein complex that possesses protein farnesyltransferase activity.
1 Q8K2I1 (/ISO)
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
1 Q02293 (/IDA)