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CATH Superfamily 1.10.730.10

Isoleucyl-tRNA Synthetase; Domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Isoleucyl-tRNA Synthetase; Domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5303: Methionine--tRNA ligase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Methionine--tRNA ligase. [EC: 6.1.1.10]
ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met).
  • In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9.
 259 A0A024BXG2 A0A024C1G8 A0A060PWJ2 A0A083YFL7 A0A086RPL9 A0A0B2E187 A0A0B2E2D9 A0A0B2E4N9 A0A0B2E9P8 A0A0B2EGQ4
(249 more...)