The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Death Domain, Fas
".
FunFam 5257: UNC-44, isoform b
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
|
5 | G5ECZ1 (/IPI) Q17490 (/IPI) Q5TYL5 (/IPI) Q5TYL6 (/IPI) Q8MQG0 (/IPI) |
|
Cytoskeletal protein binding GO:0008092
Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
|
1 | Q0KIE7 (/ISS) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Dorsal/ventral axon guidance GO:0033563
The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
|
5 | G5ECZ1 (/IGI) Q17490 (/IGI) Q5TYL5 (/IGI) Q5TYL6 (/IGI) Q8MQG0 (/IGI) |
|
Regulation of DNA recombination GO:0000018
Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.
|
1 | P59924 (/ISS) |
|
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
|
1 | P59924 (/ISS) |
|
Cytoskeletal anchoring at plasma membrane GO:0007016
A cytoskeleton organization process that directly or indirectly links cytoskeletal filaments to the plasma membrane.
|
1 | Q0KIE7 (/IDA) |
|
Body morphogenesis GO:0010171
The process in which the anatomical structures of the soma are generated and organized.
|
1 | Q17490 (/IMP) |
|
Replication fork processing GO:0031297
The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.
|
1 | P59924 (/ISS) |
|
Positive regulation of DNA-templated transcription, elongation GO:0032786
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
|
1 | P59924 (/ISS) |
|
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
|
1 | Q17490 (/IMP) |
|
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
|
1 | Q17490 (/IMP) |
|
Negative regulation of isotype switching to IgA isotypes GO:0048297
Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes.
|
1 | P59924 (/ISS) |
|
Negative regulation of DNA damage checkpoint GO:2000002
Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint.
|
1 | P59924 (/ISS) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lateral plasma membrane GO:0016328
The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells.
|
5 | G5ECZ1 (/IDA) Q17490 (/IDA) Q5TYL5 (/IDA) Q5TYL6 (/IDA) Q8MQG0 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q0KIE7 (/IDA) |
|
Spectrosome GO:0045170
A germline specific spherical organelle, rich in membrane skeletal proteins. Precursor to the fusome.
|
1 | Q0KIE7 (/IDA) |
