The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Death Domain, Fas
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1155: Caspase recruitment domain-containing protein 10

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q17RA1 (/IPI) Q9BWT7 (/IPI)
Receptor signaling complex scaffold activity GO:0030159
Functions to provide a physical support for the assembly of a multiprotein receptor signaling complex.
1 Q9BWT7 (/NAS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Activation of NF-kappaB-inducing kinase activity GO:0007250
The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.
2 P58660 (/ISS) Q9BWT7 (/ISS)
Protein complex assembly GO:0006461
The aggregation, arrangement and bonding together of a set of components to form a protein complex.
1 Q9BWT7 (/NAS)
Activation of NF-kappaB-inducing kinase activity GO:0007250
The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.
1 Q9BWT7 (/IDA)
Activation of NF-kappaB-inducing kinase activity GO:0007250
The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.
1 P58660 (/ISO)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9BWT7 (/NAS)
CBM complex GO:0032449
A protein complex comprising Carma1, Bcl10 and MALT1; plays a role in signal transduction during NF-kappaB activation.
1 Q9BWT7 (/NAS)
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