The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Transferase(Phosphotransferase) domain 1
".
FunFam 79169: Probable serine/threonine-protein kinase sky1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 26 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
23 |
A0A0B4KF69 (/IDA)
A1ZA05 (/IDA)
O35491 (/IDA)
O35492 (/IDA)
O35493 (/IDA)
O54781 (/IDA)
O70551 (/IDA)
O77306 (/IDA)
P22518 (/IDA)
P36616 (/IDA)
(13 more) |
|
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
16 |
F4J982 (/IDA)
M9MS50 (/IDA)
M9NDF9 (/IDA)
M9NDZ1 (/IDA)
M9NEI4 (/IDA)
M9NGC6 (/IDA)
M9PDA8 (/IDA)
M9PIK8 (/IDA)
P36616 (/IDA)
P49762 (/IDA)
(6 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
16 |
O54781 (/IPI)
O70551 (/IPI)
P22518 (/IPI)
P36616 (/IPI)
P49759 (/IPI)
P49760 (/IPI)
P49761 (/IPI)
P51566 (/IPI)
P51567 (/IPI)
P78362 (/IPI)
(6 more) |
|
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
10 | M9MS50 (/NAS) M9NDF9 (/NAS) M9NDZ1 (/NAS) M9NEI4 (/NAS) M9NGC6 (/NAS) M9PDA8 (/NAS) M9PIK8 (/NAS) Q8T3S1 (/NAS) Q9VNV0 (/NAS) Q9VXN5 (/NAS) |
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
7 | P49761 (/ISS) Q3SX21 (/ISS) Q5RD27 (/ISS) Q61IS6 (/ISS) Q63117 (/ISS) Q9HAZ1 (/ISS) Q9VXN5 (/ISS) |
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
4 | O54781 (/IDA) O70551 (/IDA) P78362 (/IDA) Q96SB4 (/IDA) |
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
4 | O35491 (/ISO) O54781 (/ISO) O70551 (/ISO) P22518 (/ISO) |
|
Protein tyrosine kinase activity GO:0004713
Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
|
4 | O35491 (/IDA) O35492 (/IDA) O35493 (/IDA) P22518 (/IDA) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
4 | O54781 (/IDA) O70551 (/IDA) P78362 (/IDA) Q96SB4 (/IDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
3 | P49761 (/IDA) P78362 (/IDA) Q96SB4 (/IDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
3 | O35492 (/ISO) O54781 (/ISO) O70551 (/ISO) |
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
3 | P49759 (/TAS) P49760 (/TAS) P49761 (/TAS) |
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
2 | O54781 (/ISO) O70551 (/ISO) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
2 | O54781 (/ISO) O70551 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | P49760 (/IPI) P49761 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | O35491 (/ISO) O35492 (/ISO) |
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
1 | Q5RD27 (/ISS) |
|
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
1 | Q96SB4 (/TAS) |
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
1 | P49762 (/NAS) |
|
Protein serine/threonine/tyrosine kinase activity GO:0004712
Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
|
1 | Q8IL19 (/IDA) |
|
Non-membrane spanning protein tyrosine kinase activity GO:0004715
Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein.
|
1 | P49759 (/TAS) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q5RD27 (/ISS) |
|
Kinase activity GO:0016301
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
|
1 | Q63117 (/IDA) |
|
RNA uridylyltransferase activity GO:0050265
Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1).
|
1 | P36616 (/IDA) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | O54781 (/IDA) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | P78362 (/ISS) |
There are 105 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
23 |
F4J982 (/IDA)
M9MS50 (/IDA)
M9NDF9 (/IDA)
M9NDZ1 (/IDA)
M9NEI4 (/IDA)
M9NGC6 (/IDA)
M9PDA8 (/IDA)
M9PIK8 (/IDA)
O35491 (/IDA)
O35492 (/IDA)
(13 more) |
|
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
11 |
M9MS50 (/NAS)
M9NDF9 (/NAS)
M9NDZ1 (/NAS)
M9NEI4 (/NAS)
M9NGC6 (/NAS)
M9PDA8 (/NAS)
M9PIK8 (/NAS)
P49762 (/NAS)
Q8T3S1 (/NAS)
Q9VNV0 (/NAS)
(1 more) |
|
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a neuron, across a chemical synapse, the subsequent activation of neurotransmitter receptors of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
9 | M9MS50 (/IMP) M9NDF9 (/IMP) M9NDZ1 (/IMP) M9NEI4 (/IMP) M9NGC6 (/IMP) M9PDA8 (/IMP) M9PIK8 (/IMP) Q8T3S1 (/IMP) Q9VNV0 (/IMP) |
|
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
9 | M9MS50 (/IMP) M9NDF9 (/IMP) M9NDZ1 (/IMP) M9NEI4 (/IMP) M9NGC6 (/IMP) M9PDA8 (/IMP) M9PIK8 (/IMP) Q8T3S1 (/IMP) Q9VNV0 (/IMP) |
|
Cytoskeletal matrix organization at active zone GO:0048789
The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane.
|
9 | M9MS50 (/IMP) M9NDF9 (/IMP) M9NDZ1 (/IMP) M9NEI4 (/IMP) M9NGC6 (/IMP) M9PDA8 (/IMP) M9PIK8 (/IMP) Q8T3S1 (/IMP) Q9VNV0 (/IMP) |
|
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
|
7 | O35491 (/IDA) O35492 (/IDA) O35493 (/IDA) P22518 (/IDA) P49762 (/IDA) P51567 (/IDA) P51568 (/IDA) |
|
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
|
5 | A0A0B4KF69 (/IDA) A1ZA05 (/IDA) P22518 (/IDA) Q0E965 (/IDA) Q95SW3 (/IDA) |
|
Karyosome formation GO:0030717
The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
|
5 | A0A0B4KF69 (/IMP) A1ZA05 (/IMP) P49762 (/IMP) Q0E965 (/IMP) Q95SW3 (/IMP) |
|
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
4 | O35491 (/ISO) O35492 (/ISO) O54781 (/ISO) O70551 (/ISO) |
|
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
4 | Q54UA9 (/ISS) Q5RD27 (/ISS) Q61IS6 (/ISS) Q9VXN5 (/ISS) |
|
Spindle assembly involved in female meiosis GO:0007056
The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
|
4 | A0A0B4KF69 (/IMP) A1ZA05 (/IMP) Q0E965 (/IMP) Q95SW3 (/IMP) |
|
Peptidyl-tyrosine phosphorylation GO:0018108
The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.
|
4 | O35491 (/IDA) O35492 (/IDA) O35493 (/IDA) P22518 (/IDA) |
|
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
|
4 | O54781 (/IDA) O70551 (/IDA) P78362 (/IDA) Q96SB4 (/IDA) |
|
Regulation of RNA splicing GO:0043484
Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
|
4 | O35491 (/ISO) O35492 (/ISO) O35493 (/ISO) P22518 (/ISO) |
|
Regulation of RNA splicing GO:0043484
Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
|
3 | O35491 (/ISS) Q3SX21 (/ISS) Q63117 (/ISS) |
|
Spliceosomal complex assembly GO:0000245
The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions.
|
2 | O54781 (/IDA) P78362 (/IDA) |
|
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
|
2 | O70551 (/ISS) Q5RD27 (/ISS) |
|
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | O54781 (/IDA) P78362 (/IDA) |
|
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
|
2 | O54781 (/IDA) P78362 (/IDA) |
|
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
|
2 | O54781 (/ISO) O70551 (/ISO) |
|
Regulation of RNA splicing GO:0043484
Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
|
2 | P49760 (/IDA) P49761 (/IDA) |
|
Regulation of RNA splicing GO:0043484
Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
|
2 | P49759 (/IMP) Q9HAZ1 (/IMP) |
|
Positive regulation of viral genome replication GO:0045070
Any process that activates or increases the frequency, rate or extent of viral genome replication.
|
2 | P78362 (/IDA) Q96SB4 (/IDA) |
|
Positive regulation of viral genome replication GO:0045070
Any process that activates or increases the frequency, rate or extent of viral genome replication.
|
2 | O54781 (/ISO) O70551 (/ISO) |
|
Negative regulation of viral genome replication GO:0045071
Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.
|
2 | P78362 (/IDA) Q96SB4 (/IDA) |
|
Negative regulation of viral genome replication GO:0045071
Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.
|
2 | O54781 (/ISO) O70551 (/ISO) |
|
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
2 | P78362 (/IC) Q96SB4 (/IC) |
|
Regulation of mRNA splicing, via spliceosome GO:0048024
Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.
|
2 | P78362 (/TAS) Q96SB4 (/TAS) |
|
Positive regulation of mRNA splicing, via spliceosome GO:0048026
Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism.
|
2 | P36616 (/IMP) Q10156 (/IMP) |
|
Regulation of mRNA processing GO:0050684
Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.
|
2 | O70551 (/IDA) Q96SB4 (/IDA) |
|
Muscle tissue development GO:0060537
The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.
|
2 | B8Y466 (/ISS) Q9UPE1 (/ISS) |
|
Spliceosomal complex assembly GO:0000245
The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions.
|
1 | O54781 (/ISO) |
|
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
|
1 | P49762 (/IMP) |
|
Cell separation after cytokinesis GO:0000920
The process of physically separating progeny cells after cytokinesis; this may involve enzymatic digestion of septum or cell wall components.
|
1 | Q10156 (/IMP) |
|
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
1 | O54781 (/IDA) |
|
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
1 | P78362 (/ISS) |
|
Startle response GO:0001964
An action or movement due to the application of a sudden unexpected stimulus.
|
1 | P49762 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | P51566 (/TAS) |
|
MRNA splice site selection GO:0006376
Selection of a splice site by components of the assembling spliceosome.
|
1 | Q03656 (/IGI) |
|
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
|
1 | P51567 (/IDA) |
|
Cellular ion homeostasis GO:0006873
Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
|
1 | Q03656 (/IMP) |
|
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
1 | F4J982 (/IDA) |
|
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
|
1 | Q96SB4 (/IDA) |
|
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
|
1 | O70551 (/ISO) |
|
Blastoderm segmentation GO:0007350
The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.
|
1 | P49762 (/IMP) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
1 | P49762 (/IMP) |
|
Skeletal muscle tissue development GO:0007519
The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
|
1 | Q9Z0G2 (/IMP) |
|
Sex differentiation GO:0007548
The establishment of the sex of an organism by physical differentiation.
|
1 | P49762 (/IGI) |
|
Sex differentiation GO:0007548
The establishment of the sex of an organism by physical differentiation.
|
1 | P49762 (/IMP) |
|
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
1 | P49759 (/TAS) |
|
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | O54781 (/ISO) |
|
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
|
1 | O54781 (/ISO) |
|
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
|
1 | Q96SB4 (/TAS) |
|
Protein secretion GO:0009306
The controlled release of proteins from a cell.
|
1 | P49762 (/IMP) |
|
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
1 | Q03563 (/IGI) |
|
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
1 | Q61IS6 (/ISS) |
|
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
|
1 | O35491 (/IDA) |
|
Response to ionizing radiation GO:0010212
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
|
1 | P49760 (/IMP) |
|
Response to ionizing radiation GO:0010212
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
|
1 | O35491 (/ISO) |
|
Response to ionizing radiation GO:0010212
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
|
1 | O35491 (/ISS) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | O54781 (/IDA) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | P78362 (/ISS) |
|
Peptidyl-threonine phosphorylation GO:0018107
The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
|
1 | P22518 (/IDA) |
|
Cellular cation homeostasis GO:0030003
Any process involved in the maintenance of an internal steady state of cations at the level of a cell.
|
1 | Q03656 (/IMP) |
|
Establishment of cell polarity GO:0030010
The specification and formation of anisotropic intracellular organization or cell growth patterns.
|
1 | C8VU80 (/IMP) |
|
Negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle GO:0031658
Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.
|
1 | Q10156 (/IMP) |
|
Locomotion involved in locomotory behavior GO:0031987
Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
|
1 | P49762 (/IMP) |
|
Response to retinoic acid GO:0032526
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
|
1 | O35491 (/IDA) |
|
Negative regulation of MyD88-dependent toll-like receptor signaling pathway GO:0034125
Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.
|
1 | P49762 (/IMP) |
|
Regulation of ascospore formation GO:0034307
Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae.
|
1 | C8VU80 (/IMP) |
|
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
1 | Q10156 (/IMP) |
|
Nuclear speck organization GO:0035063
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized.
|
1 | O54781 (/IDA) |
|
Nuclear speck organization GO:0035063
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized.
|
1 | P78362 (/ISS) |
|
Salivary gland cell autophagic cell death GO:0035071
The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis.
|
1 | P49762 (/IEP) |
|
Sperm chromatin condensation GO:0035092
The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication.
|
1 | Q96SB4 (/TAS) |
|
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
|
1 | Q5RD27 (/ISS) |
|
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
|
1 | P36616 (/NAS) |
|
Growth GO:0040007
The increase in size or mass of an entire organism, a part of an organism or a cell.
|
1 | Q586G9 (/IMP) |
|
Compound eye photoreceptor development GO:0042051
The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure.
|
1 | P49762 (/IEP) |
|
Compound eye photoreceptor development GO:0042051
The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure.
|
1 | P49762 (/IMP) |
|
Positive regulation of protein import into nucleus GO:0042307
Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.
|
1 | Q03656 (/IMP) |
|
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | Q03656 (/IMP) |
|
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
|
1 | O54781 (/IDA) |
|
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
|
1 | P78362 (/ISS) |
|
Positive regulation of viral genome replication GO:0045070
Any process that activates or increases the frequency, rate or extent of viral genome replication.
|
1 | O54781 (/ISS) |
|
Negative regulation of viral genome replication GO:0045071
Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.
|
1 | O54781 (/ISS) |
|
Regulation of cell differentiation GO:0045595
Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
|
1 | Q8IL19 (/TAS) |
|
Negative regulation of gluconeogenesis GO:0045721
Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.
|
1 | O35491 (/IMP) |
|
Negative regulation of gluconeogenesis GO:0045721
Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.
|
1 | P49760 (/ISS) |
|
Positive regulation of cell cycle GO:0045787
Any process that activates or increases the rate or extent of progression through the cell cycle.
|
1 | O54781 (/IDA) |
|
Positive regulation of cell cycle GO:0045787
Any process that activates or increases the rate or extent of progression through the cell cycle.
|
1 | P78362 (/ISS) |
|
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
|
1 | P49760 (/ISS) |
|
Regulation of nucleocytoplasmic transport GO:0046822
Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
|
1 | P36616 (/IMP) |
|
Autophagic cell death GO:0048102
A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.
|
1 | P49762 (/IEP) |
|
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
|
1 | P49762 (/IMP) |
|
Compound eye development GO:0048749
The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
|
1 | P49762 (/IMP) |
|
Brain morphogenesis GO:0048854
The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
1 | P49762 (/IMP) |
|
Regulation of mRNA processing GO:0050684
Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.
|
1 | O70551 (/ISO) |
|
Regulation of mRNA processing GO:0050684
Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.
|
1 | Q5RD27 (/ISS) |
|
Muscle tissue development GO:0060537
The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.
|
1 | Q9Z0G2 (/IMP) |
|
Regulation of conidiophore development GO:0070793
Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
|
1 | C8VU80 (/IMP) |
|
Regulation of cleistothecium development GO:0070796
Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
|
1 | C8VU80 (/IMP) |
|
Negative regulation of protein localization to nucleus GO:1900181
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus.
|
1 | P36616 (/IMP) |
|
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
|
1 | P36616 (/IMP) |
|
Negative regulation of male germ cell proliferation GO:2000255
Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation.
|
1 | P49762 (/IMP) |
There are 28 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
17 |
A0A024R704 (/IDA)
H3BLV9 (/IDA)
H7C5L6 (/IDA)
O35491 (/IDA)
O35492 (/IDA)
O35493 (/IDA)
O54781 (/IDA)
O77306 (/IDA)
P22518 (/IDA)
P36616 (/IDA)
(7 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
9 | A0A0B4KF69 (/ISS) A1ZA05 (/ISS) O70551 (/ISS) Q0E965 (/ISS) Q3SX21 (/ISS) Q5RD27 (/ISS) Q63117 (/ISS) Q95SW3 (/ISS) Q9VXN5 (/ISS) |
|
Presynaptic active zone GO:0048786
A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.
|
9 | M9MS50 (/IDA) M9NDF9 (/IDA) M9NDZ1 (/IDA) M9NEI4 (/IDA) M9NGC6 (/IDA) M9PDA8 (/IDA) M9PIK8 (/IDA) Q8T3S1 (/IDA) Q9VNV0 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | D4ADG3 (/IDA) O54781 (/IDA) O77306 (/IDA) P36616 (/IDA) P49762 (/IDA) P78362 (/IDA) Q03656 (/IDA) Q96SB4 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
7 | A0A0B4KF69 (/ISS) A1ZA05 (/ISS) O70551 (/ISS) Q0E965 (/ISS) Q5RD27 (/ISS) Q95SW3 (/ISS) Q9VXN5 (/ISS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
6 | A0A024R704 (/IDA) A8K7I0 (/IDA) B1AVT0 (/IDA) P49760 (/IDA) P49761 (/IDA) P78362 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
6 | A0A024R704 (/IDA) H3BLV9 (/IDA) H7C5L6 (/IDA) P36616 (/IDA) P78362 (/IDA) Q96SB4 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | O35491 (/ISO) O35492 (/ISO) O54781 (/ISO) O70551 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | O35491 (/ISO) O35492 (/ISO) O54781 (/ISO) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
3 | A0A024R704 (/IDA) H7C5L6 (/IDA) P78362 (/IDA) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
3 | A8K7I0 (/IDA) B1AVT0 (/IDA) P49760 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | O54781 (/ISO) O70551 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | O54781 (/ISO) O70551 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | H3BLV9 (/IDA) Q96SB4 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P49762 (/IC) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q10156 (/IMP) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q96SB4 (/TAS) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | O54781 (/ISO) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | P49762 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O70551 (/ISO) |
|
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
|
1 | Q9FYC5 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | P49761 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | O35492 (/ISO) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
1 | O35491 (/ISO) |
|
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
|
1 | P36616 (/IDA) |
|
Mitotic spindle pole body GO:0044732
The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
|
1 | P36616 (/IDA) |
|
Intermediate filament cytoskeleton GO:0045111
Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.
|
1 | P49761 (/IDA) |
|
Intermediate filament cytoskeleton GO:0045111
Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.
|
1 | O35492 (/ISO) |