The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Histone, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 5635: Probable transcription factor Hap5a

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
9 Q4PSE2 (/ISS) Q8L4B2 (/ISS) Q8LCG7 (/ISS) Q9FGP6 (/ISS) Q9FGP7 (/ISS) Q9FGP8 (/ISS) Q9FMV5 (/ISS) Q9SMP0 (/ISS) Q9ZVL3 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 A6BLW4 (/IPI) Q02516 (/IPI) Q655V5 (/IPI) Q8L4B2 (/IPI) Q8LCG7 (/IPI) Q9FMV5 (/IPI) Q9SMP0 (/IPI) Q9XE33 (/IPI) Q9ZVL3 (/IPI)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 A0A1D8PN26 (/IMP) C8V0B5 (/IMP)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
2 A0A1D8PN26 (/IMP) C8V0B5 (/IMP)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 C8V0B5 (/IDA) Q8L4B2 (/IDA)
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1 P79007 (/IC)
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1 P79007 (/IMP)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 C8V0B5 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 A0A1D8PN26 (/IGI)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 P79007 (/ISO)

There are 36 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of photomorphogenesis GO:2000306
Any process that activates or increases the frequency, rate or extent of photomorphogenesis.
4 Q8L4B2 (/IMP) Q9FMV5 (/IMP) Q9SMP0 (/IMP) Q9ZVL3 (/IMP)
Abscisic acid-activated signaling pathway GO:0009738
A series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.
3 Q8L4B2 (/IGI) Q9FMV5 (/IGI) Q9ZVL3 (/IGI)
Gibberellic acid mediated signaling pathway GO:0009740
A series of molecular signals mediated by the detection of gibberellic acid.
3 Q8L4B2 (/IGI) Q9FMV5 (/IGI) Q9ZVL3 (/IGI)
Regulation of seed germination GO:0010029
Any process that modulates the frequency, rate or extent of seed germination.
3 Q8L4B2 (/IGI) Q9FMV5 (/IGI) Q9ZVL3 (/IGI)
Regulation of carbohydrate metabolic process GO:0006109
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
2 A0A1D8PN26 (/IMP) C8V0B5 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 Q8LCG7 (/ISS) Q9SMP0 (/ISS)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 Q8LCG7 (/IDA) Q9SMP0 (/IDA)
Negative regulation of long-day photoperiodism, flowering GO:0048579
Any process that stops, prevents or reduces long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
2 A6BLW4 (/IMP) Q655V5 (/IMP)
Carbon catabolite activation of transcription from RNA polymerase II promoter GO:0000436
Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q02516 (/IMP)
Regulation of carbohydrate metabolic process GO:0006109
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
1 A0A1D8PN26 (/IGI)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
1 C8V0B5 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 A0A1D8PN26 (/IGI)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 A0A1D8PN26 (/IMP)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
1 Q9W3V9 (/IMP)
Abscisic acid-activated signaling pathway GO:0009738
A series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.
1 Q9FMV5 (/IMP)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q9FMV5 (/IMP)
Nucleosome positioning GO:0016584
Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.
1 C8V0B5 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 A0A1D8PN26 (/IMP)
Regulation of transcription from RNA polymerase II promoter in response to iron ion starvation GO:0033217
Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.
1 A0A1D8PN26 (/IMP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 A0A1D8PN26 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 A0A1D8PN26 (/IMP)
Filamentous growth of a population of unicellular organisms in response to chemical stimulus GO:0036171
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus.
1 A0A1D8PN26 (/IMP)
Cellular response to neutral pH GO:0036244
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
1 A0A1D8PN26 (/IMP)
Regulation of cellular respiration GO:0043457
Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds.
1 Q02516 (/IGI)
Regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0043619
Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 A0A1D8PN26 (/IMP)
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
1 A0A1D8PN26 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 C8V0B5 (/IMP)
Regulation of long-day photoperiodism, flowering GO:0048586
Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
1 Q9FMV5 (/IGI)
Positive regulation of protein metabolic process GO:0051247
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
1 Q9FMV5 (/IMP)
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
1 A0A1D8PN26 (/IMP)
Cellular response to alkaline pH GO:0071469
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.
1 A0A1D8PN26 (/IMP)
Positive regulation of filamentous growth GO:0090033
Any process that increases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 A0A1D8PN26 (/IMP)
Positive regulation of filamentous growth of a population of unicellular organisms in response to starvation GO:1900436
Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
1 A0A1D8PN26 (/IMP)
Negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH GO:1900441
Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.
1 A0A1D8PN26 (/IMP)
Positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:1900445
Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
1 A0A1D8PN26 (/IMP)
Negative regulation of starch metabolic process GO:2000905
Any process that stops, prevents or reduces the frequency, rate or extent of starch metabolic process.
1 Q9FMV5 (/IMP)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 A6BLW4 (/IDA) O59849 (/IDA) P79007 (/IDA) Q655V5 (/IDA) Q8L4B2 (/IDA) Q8LCG7 (/IDA) Q9SMP0 (/IDA) Q9XE33 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 A6BLW4 (/IDA) P79007 (/IDA) Q655V5 (/IDA) Q8L4B2 (/IDA) Q8LCG7 (/IDA) Q9XE33 (/IDA)
CCAAT-binding factor complex GO:0016602
A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.
4 A0A1D8PN26 (/IDA) C8V0B5 (/IDA) Q02516 (/IDA) Q9W3V9 (/IDA)
CCAAT-binding factor complex GO:0016602
A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.
3 Q557I1 (/ISS) Q8LCG7 (/ISS) Q9SMP0 (/ISS)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
1 P79007 (/NAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9FMV5 (/IPI)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8L4B2 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9FMV5 (/IPI)
CCAAT-binding factor complex GO:0016602
A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.
1 A0A1D8PN26 (/IGI)
CCAAT-binding factor complex GO:0016602
A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.
1 A0A1D8PN26 (/IMP)
CCAAT-binding factor complex GO:0016602
A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.
1 Q02516 (/IPI)
CCAAT-binding factor complex GO:0016602
A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.
1 P79007 (/ISO)