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CATH Superfamily 1.10.20.10

Histone, subunit A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Histone, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5635: Probable transcription factor Hap5a

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
DNA-directed DNA polymerase. [EC: 2.7.7.7]
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
  • Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.
  • Cannot initiate a chain de novo.
  • Requires a primer which may be DNA or RNA.
  • See also EC 2.7.7.49.
 4 G0QK34 G0QK34 G0QKW4 G0QKW4
2-isopropylmalate synthase. [EC: 2.3.3.13]
Acetyl-CoA + 3-methyl-2-oxobutanoate + H(2)O = (2S)-2-isopropylmalate + CoA.
  • Formerly EC 4.1.3.12.
 2 M5BMI9 M5BMI9
Non-specific serine/threonine protein kinase. [EC: 2.7.11.1]
ATP + a protein = ADP + a phosphoprotein.
  • This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.
  • Formerly EC 2.7.1.37 and EC 2.7.1.70.
 2 G0QK34 G0QK34
Type 1 galactoside alpha-(1,2)-fucosyltransferase. [EC: 2.4.1.69]
GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D- glucosaminyl-R = GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N- acetyl-beta-D-glucosaminyl-R.
  • The enzyme acts on a glycoconjugates where the substituent group is a glycoprotein or glycosphingolipid.
  • The recognized moiety of the substrate is known as a type 1 histo- blood group antigen precursor disaccharide, and the action of the enzyme produces an H type 1 antigen.
  • The enzyme from the bacterium Helicobacter pylori cannot act on type 2 substrates (see EC 2.4.1.344).
  • Formerly EC 2.4.1.89.
 2 G0QK34 G0QK34
Malate dehydrogenase. [EC: 1.1.1.37]
(S)-malate + NAD(+) = oxaloacetate + NADH.
  • Also oxidizes some other 2-hydroxydicarboxylic acids.
 2 A0A0L1I2T4 A0A0L1I2T4
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