View in Gene3D

CATH Superfamily 1.10.150.20

5' to 3' exonuclease, C-terminal subdomain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
5' to 3' exonuclease, C-terminal subdomain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 27233: DNA repair protein RAD51

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Non-specific serine/threonine protein kinase. [EC: 2.7.11.1]
ATP + a protein = ADP + a phosphoprotein.
  • This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.
  • Formerly EC 2.7.1.37 and EC 2.7.1.70.
 4 B0ENA1 B0ENA1 B7P430 B7P430
Adenosinetriphosphatase. [EC: 3.6.1.3]
ATP + H(2)O = ADP + phosphate.
  • Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39.
  • The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA.
  • Formerly EC 3.6.1.4.
 4 B4M6I5 B4M6I5 B4NJK2 B4NJK2
Methylated-DNA--[protein]-cysteine S-methyltransferase. [EC: 2.1.1.63]
DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine.
  • This protein is involved in the repair of alkylated DNA.
  • It acts only on the alkylated DNA (cf. EC 3.2.2.20 and EC 3.2.2.21).
  • This enzyme catalyzes only one turnover and therefore is not strictly catalytic.
 4 B7PQG9 B7PQG9 M5CEP2 M5CEP2
Calcium-transporting ATPase. [EC: 3.6.3.8]
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • This enzyme family comprises three types of Ca(2+)-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum and in Saccharomyces cerevisiae.
  • The first and third transport one ion per ATP hydrolyzed, whereas the second transports two ions.
  • Formerly EC 3.6.1.38.
 2 B0EJ35 B0EJ35