CATH Superfamily 1.10.10.10
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".
FunFam 266417: O-methyltransferase family protein, expressed
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 29 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Acetylserotonin O-methyltransferase activity GO:0017096
Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.
|
9 | B3GSH5 (/IDA) D3KU66 (/IDA) D3KU67 (/IDA) P46597 (/IDA) Q6EPG8 (/IDA) Q6ZD89 (/IDA) Q8VWG4 (/IDA) Q8VWJ6 (/IDA) Q9T003 (/IDA) |
O-methyltransferase activity GO:0008171
Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
|
5 | A8QW52 (/IDA) A8QW53 (/IDA) Q6WUC1 (/IDA) Q6WUC2 (/IDA) Q8T638 (/IDA) |
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
|
4 | A8QW52 (/IDA) A8QW53 (/IDA) B3GSH5 (/IDA) Q8T638 (/IDA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | O95671 (/IPI) Q9LPU5 (/IPI) Q9LPU8 (/IPI) |
Acetylserotonin O-methyltransferase activity GO:0017096
Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.
|
3 | P10950 (/ISS) Q8HZJ0 (/ISS) Q92056 (/ISS) |
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
|
2 | Q9LPU5 (/IDA) Q9LPU7 (/IDA) |
Acetylserotonin O-methyltransferase activity GO:0017096
Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.
|
2 | D3KU66 (/IMP) D3KU67 (/IMP) |
Luteolin O-methyltransferase activity GO:0030744
Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+).
|
2 | Q6ZD89 (/IDA) Q9FK25 (/IDA) |
Isoflavone 4'-O-methyltransferase activity GO:0030746
Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone.
|
2 | Q84KK4 (/IDA) Q84KK6 (/IDA) |
Myricetin 3'-O-methyltransferase activity GO:0033799
Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.
|
2 | Q8GSN1 (/IDA) Q9FK25 (/IDA) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | Q6WUC1 (/IDA) Q6WUC2 (/IDA) |
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
|
1 | O49010 (/IDA) |
O-methyltransferase activity GO:0008171
Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
|
1 | Q9SRD4 (/IMP) |
O-methyltransferase activity GO:0008171
Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
|
1 | P46597 (/TAS) |
S-methyltransferase activity GO:0008172
Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule.
|
1 | Q1WMA5 (/IDA) |
S-methyltransferase activity GO:0008172
Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule.
|
1 | P46597 (/TAS) |
Licodione 2'-O-methyltransferase activity GO:0030751
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + licodione = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H(+).
|
1 | P93324 (/IDA) |
Quercetin 3-O-methyltransferase activity GO:0030755
Catalysis of the reaction: S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxy-flavone.
|
1 | Q9FK25 (/IDA) |
8-hydroxyquercitin 8-O-methyltransferase activity GO:0030761
Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+).
|
1 | Q6VMW0 (/IDA) |
11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity GO:0030766
Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline.
|
1 | B0EXJ8 (/IDA) |
Isoflavone 7-O-methyltransferase activity GO:0033800
Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone.
|
1 | Q84KK5 (/IDA) |
Isoliquiritigenin 2'-O-methyltransferase activity GO:0033802
Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H(+).
|
1 | P93324 (/IDA) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | P46597 (/IPI) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | B0EXJ8 (/IDA) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P46597 (/IPI) |
Caffeate O-methyltransferase activity GO:0047763
Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.
|
1 | I1I1F5 (/IDA) |
Caffeate O-methyltransferase activity GO:0047763
Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.
|
1 | Q6ZD89 (/IGC) |
Caffeate O-methyltransferase activity GO:0047763
Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.
|
1 | Q9FK25 (/IMP) |
Caffeate O-methyltransferase activity GO:0047763
Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.
|
1 | Q9FK25 (/ISS) |
There are 29 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Melatonin biosynthetic process GO:0030187
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
|
8 | B3GSH5 (/IDA) D3KU66 (/IDA) D3KU67 (/IDA) P46597 (/IDA) Q6EPG8 (/IDA) Q8VWG4 (/IDA) Q8VWJ6 (/IDA) Q9T003 (/IDA) |
Methylation GO:0032259
The process in which a methyl group is covalently attached to a molecule.
|
4 | A8QW52 (/IDA) A8QW53 (/IDA) B0EXJ8 (/IDA) Q6VMW0 (/IDA) |
Alkaloid biosynthetic process GO:0009821
The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases).
|
3 | B0EXJ8 (/IDA) Q6WUC1 (/IDA) Q6WUC2 (/IDA) |
Melatonin biosynthetic process GO:0030187
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
|
3 | D3KU66 (/IMP) D3KU67 (/IMP) Q6ZD89 (/IMP) |
Melatonin biosynthetic process GO:0030187
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
|
3 | P10950 (/ISS) Q8HZJ0 (/ISS) Q92056 (/ISS) |
Isoflavonoid phytoalexin biosynthetic process GO:0009701
The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.
|
2 | Q84KK4 (/IDA) Q84KK6 (/IDA) |
Indole glucosinolate metabolic process GO:0042343
The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan.
|
2 | Q9LPU5 (/IDA) Q9LPU7 (/IDA) |
Flavonol biosynthetic process GO:0051555
The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.
|
2 | Q6ZD89 (/IDA) Q9FK25 (/IDA) |
Negative regulation of male gonad development GO:2000019
Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development.
|
2 | D3KU66 (/IMP) D3KU67 (/IMP) |
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome.
|
1 | P46597 (/TAS) |
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
1 | Q84N28 (/IDA) |
Response to herbicide GO:0009635
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants.
|
1 | O49010 (/IDA) |
Isoflavonoid biosynthetic process GO:0009717
The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.
|
1 | Q84KK5 (/IDA) |
Response to ethylene GO:0009723
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
|
1 | Q84N28 (/IDA) |
Response to salicylic acid GO:0009751
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.
|
1 | Q84N28 (/IDA) |
Indole glucosinolate biosynthetic process GO:0009759
The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.
|
1 | Q9SRD4 (/IMP) |
Lignin biosynthetic process GO:0009809
The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers.
|
1 | Q6ZD89 (/IDA) |
Lignin biosynthetic process GO:0009809
The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers.
|
1 | Q9FK25 (/IMP) |
Lignin biosynthetic process GO:0009809
The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers.
|
1 | O49010 (/TAS) |
Flavonoid metabolic process GO:0009812
The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins.
|
1 | Q6VMW0 (/IDA) |
Sporulation resulting in formation of a cellular spore GO:0030435
The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
|
1 | Q8T638 (/IMP) |
DIF-1 biosynthetic process GO:0031148
The chemical reactions and pathways resulting in the formation of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells.
|
1 | Q8T638 (/IDA) |
Sorocarp stalk cell differentiation GO:0031149
The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum.
|
1 | Q8T638 (/IMP) |
Culmination involved in sorocarp development GO:0031154
The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.
|
1 | Q8T638 (/IMP) |
Sorocarp morphogenesis GO:0031288
The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum.
|
1 | Q8T638 (/IMP) |
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
|
1 | Q84N28 (/IDA) |
Secondary metabolite biosynthetic process GO:0044550
The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
|
1 | Q4WYG1 (/IMP) |
Regulation of cell differentiation GO:0045595
Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
|
1 | Q8T638 (/IMP) |
Indolalkylamine biosynthetic process GO:0046219
The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.
|
1 | P46597 (/TAS) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
6 | B0EXJ8 (/IDA) Q6EPG8 (/IDA) Q8VWG4 (/IDA) Q8VWJ6 (/IDA) Q9FK25 (/IDA) Q9T003 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | O95671 (/IDA) Q9MAP0 (/IDA) |
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
1 | Q8T638 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9FK25 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P46597 (/TAS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9FK25 (/IDA) |
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
|
1 | Q9FK25 (/IDA) |