CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Fibroblast growth factor receptor

Enzyme Information

2.7.10.1
Receptor protein-tyrosine kinase.
based on mapping to UniProt P21803
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P21803
FGFR2_MOUSE
Mus musculus
Fibroblast growth factor receptor 2

PDB Structure

PDB 4HWU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the Ig-C2 type 1 domain from mouse FGFR2 [NYSGRC-005912]
Kumar, P.R., Nathenson, S.G., Almo, S.C.
to be published