CATH Domain 4bzyA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.80	Glycosidases

Domain Context

CATH Clusters

Superfamily	Glycosidases
Functional Family	1,4-alpha-glucan branching enzyme

Enzyme Information

2.4.1.18

1,4-alpha-glucan branching enzyme.

based on mapping to UniProt Q04446

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.

-!- Converts amylose into amylopectin. -!- The description (official name) requires a qualification depending on the product, glycogen or amylopectin, e.g. glycogen branching enzyme, amylopectin branching enzyme. -!- The latter has frequently been termed Q-enzyme.

UniProtKB Entries (1)

Q04446

GLGB_HUMAN

Homo sapiens

1,4-alpha-glucan-branching enzyme

PDB Structure

PDB	4BZY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Basis of Glycogen Branching Enzyme Deficiency and Pharmacologic Rescue by Rational Peptide Design. Froese, D.S., Michaeli, A., Mccorvie, T.J., Krojer, T., Sasi, M., Melaev, E., Goldblum, A., Zatsepin, M., Lossos, A., Alvarez, R., Escriba, P.V., Minaissan, B.A., von Delft, F., Kakhlon, O., Yue, W.W. Hum.Mol.Genet.