CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Uridine cytidine kinase I, putative

Enzyme Information

2.7.1.48
Uridine kinase.
based on mapping to UniProt Q5SKR5
(1) ATP + uridine = ADP + UMP. (2) ATP + cytidine = ADP + CMP.
-!- Cytidine can act as acceptor. -!- GTP and ITP can act as donors.

UniProtKB Entries (1)

Q5SKR5
URK_THET8
Thermus thermophilus HB8
Uridine kinase

PDB Structure

PDB 3W34
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Biochemical Studies on the Reaction Mechanism of Uridine-Cytidine Kinase
Tomoike, F., Nakagawa, N., Kuramitsu, S., Masui, R.
Protein J.