CATH Classification

Domain Context

CATH Clusters

Superfamily NADP-dependent oxidoreductase domain
Functional Family 2,5-diketo-D-gluconic acid reductase

Enzyme Information

1.1.1.274
2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming).
based on mapping to UniProt Q92RC6
2-dehydro-D-gluconate + NADP(+) = 2,5-didehydro-D-gluconate + NADPH.
-!- The enzyme is involved in the catabolism of 2,5-didehydrogluconate. -!- cf. EC 1.1.1.346.

UniProtKB Entries (1)

Q92RC6
Q92RC6_RHIME
Sinorhizobium meliloti 1021
Putative 2,5-diketo-D-gluconic acid reductase B

PDB Structure

PDB 3UP8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of a putative 2,5-diketo-D-gluconic acid reductase B
Eswaramoorthy, S., Almo, S.C., Swaminathan, S.
To be Published