CATH Domain 3sepA04

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	Beta-galactosidase 1

Enzyme Information

3.2.1.23

Beta-galactosidase.

based on mapping to UniProt P00722

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D- galactosides.

-!- Some enzymes in this group hydrolyze alpha-L-arabinosides; some animal enzymes also hydrolyze beta-D-fucosides and beta-D-glucosides (cf. EC 3.2.1.108).

UniProtKB Entries (1)

P00722

BGAL_ECOLI

Escherichia coli K-12

Beta-galactosidase

PDB Structure

PDB	3SEP
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Ser-796 of Beta-Galactosidase (E. coli) Plays a Key Role in Maintaining an Optimum Balance between the Opened and Closed Conformations of the Catalytically Important Active Site Loop Jancewicz, L.J., Wheatley, R.W., Sutendra, G., Lee, M., Fraser, M.E., Huber, R.E. Arch.Biochem.Biophys.