CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent dethiobiotin synthetase BioD

Enzyme Information

6.3.3.3
Dethiobiotin synthase.
based on mapping to UniProt Q5NGB5
ATP + 7,8-diaminononanoate + CO(2) = ADP + phosphate + dethiobiotin.
-!- CTP has half the activity of ATP.

UniProtKB Entries (1)

Q5NGB5
BIOD_FRATT
Francisella tularensis subsp. tularensis SCHU S4
ATP-dependent dethiobiotin synthetase BioD

PDB Structure

PDB 3OF5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of a Dethiobiotin Synthetase from Francisella tularensis subsp. tularensis SCHU S4
Brunzelle, J.S., Skarina, T., Gordon, E., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases
TO BE PUBLISHED