CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.29 | PH-domain like |
|
2.30.29.30 | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
Domain Context
CATH Clusters
| Superfamily | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| Functional Family | Dynamin 2, isoform CRA_b |
Enzyme Information
| 3.6.5.5 |
Dynamin GTPase.
based on mapping to UniProt P50570
GTP + H(2)O = GDP + phosphate.
-!- An enzyme with a molecular mass of about 100 kDa that is involved in endocytosis and is instrumental in pinching off membrane vesicles. -!- Formerly EC 3.6.1.50.
|
UniProtKB Entries (1)
| P50570 |
DYN2_HUMAN
Homo sapiens
Dynamin-2
|
PDB Structure
| PDB | 2YS1 |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution structure of the PH domain of Dynamin-2 from human
To be Published
|