CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.470 | D-amino Acid Aminotransferase; Chain A, domain 1 |
|
3.30.470.20 | ATP-grasp fold, B domain |
Domain Context
CATH Clusters
| Superfamily | ATP-grasp fold, B domain |
| Functional Family | Acetyl-CoA carboxylase, isoform A |
Enzyme Information
| 6.3.4.14 |
Biotin carboxylase.
based on mapping to UniProt Q13085
ATP + biotin-[carboxyl-carrier-protein] + HCO(3)(-) = ADP + phosphate + carboxy-biotin-[carboxyl-carrier-protein].
|
| 6.4.1.2 |
Acetyl-CoA carboxylase.
based on mapping to UniProt Q13085
ATP + acetyl-CoA + HCO(3)(-) = ADP + phosphate + malonyl-CoA.
-!- Also catalyzes transcarboxylation; the plant enzyme also carboxylates propanoyl-CoA and butanoyl-CoA.
|
UniProtKB Entries (1)
| Q13085 |
ACACA_HUMAN
Homo sapiens
Acetyl-CoA carboxylase 1
|
PDB Structure
| PDB | 2YL2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of Human Acetyl-Coa Carboxylase 1, Biotin Carboxylase (Bc) Domain
To be Published
|