CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Bifunctional coenzyme A synthase |
Enzyme Information
| 2.7.7.3 |
Pantetheine-phosphate adenylyltransferase.
based on mapping to UniProt Q9DBL7
ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA.
-!- The enzyme from several bacteria (e.g. Escherichia coli, Bacillus subtilis and Haemophilus influenzae) has been shown to be bifunctional and also to possess the activity of EC 2.3.1.157.
|
| 2.7.1.24 |
Dephospho-CoA kinase.
based on mapping to UniProt Q9DBL7
ATP + 3'-dephospho-CoA = ADP + CoA.
|
UniProtKB Entries (1)
| Q9DBL7 |
COASY_MOUSE
Mus musculus
Bifunctional coenzyme A synthase
|
PDB Structure
| PDB | 2F6R |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of Bifunctional coenzyme A synthase (CoA synthase) (18044849) from MUS MUSCULUS at 1.70 A resolution
To be published
|