CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Uridine cytidine kinase I, putative |
Enzyme Information
| 2.7.1.48 |
Uridine kinase.
based on mapping to UniProt Q9BZX2
(1) ATP + uridine = ADP + UMP. (2) ATP + cytidine = ADP + CMP.
-!- Cytidine can act as acceptor. -!- GTP and ITP can act as donors.
|
UniProtKB Entries (1)
| Q9BZX2 |
UCK2_HUMAN
Homo sapiens
Uridine-cytidine kinase 2
|
PDB Structure
| PDB | 1UDW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase
STRUCTURE
|