CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.60 | Sandwich | |
2.60.40 | Immunoglobulin-like | |
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
Superfamily | Immunoglobulins |
Functional Family | Hemocyte protein-glutamine gamma-glutamyltransferase, putative |
Enzyme Information
2.3.2.13 |
Protein-glutamine gamma-glutamyltransferase.
based on mapping to UniProt P21980
Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH(3).
-!- The gamma-carboxymide groups of peptide-bound glutamine residues act as acyl donors, and the 6-amino-groups of protein- and peptide-bound lysine residues act as acceptors, to give intra- and inter-molecular N(6)-(5-glutamyl)lysine crosslinks.
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UniProtKB Entries (1)
P21980 |
TGM2_HUMAN
Homo sapiens
Protein-glutamine gamma-glutamyltransferase 2
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PDB Structure
PDB | 1KV3 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity.
Proc.Natl.Acad.Sci.USA
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