CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Zeta toxin |
Enzyme Information
| 2.7.1.176 |
UDP-N-acetylglucosamine kinase.
based on mapping to UniProt Q54944
ATP + UDP-N-acetyl-alpha-D-glucosamine = ADP + UDP-N-acetyl-alpha-D- glucosamine 3'-phosphate.
-!- Toxic component of a toxin-antitoxin (TA) module. -!- The phosphorylation of UDP-N-acetyl-alpha-D-glucosamine results in the inhibition of EC 2.5.1.7, which is then blocked. -!- Phosphorylation is inhibited by cognate epsilon antitoxin. -!- Formerly EC 2.7.1.n7.
|
UniProtKB Entries (1)
| Q57231 |
EATX_STRPY
Streptococcus pyogenes
Antitoxin epsilon
|
PDB Structure
| PDB | 1GVN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of the Plasmid Maintenance System Epsilon /Zeta : Functional Mechanism of Toxin Zeta and Inactivation by Epsilon 2 Zeta 2 Complex Formation
Proc.Natl.Acad.Sci.USA
|