CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
| Superfamily | Immunoglobulins |
| Functional Family | Coagulation factor XIII A chain |
Enzyme Information
| 2.3.2.13 |
Protein-glutamine gamma-glutamyltransferase.
based on mapping to UniProt P00488
Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH(3).
-!- The gamma-carboxymide groups of peptide-bound glutamine residues act as acyl donors, and the 6-amino-groups of protein- and peptide-bound lysine residues act as acceptors, to give intra- and inter-molecular N(6)-(5-glutamyl)lysine crosslinks.
|
UniProtKB Entries (1)
| P00488 |
F13A_HUMAN
Homo sapiens
Coagulation factor XIII A chain
|
PDB Structure
| PDB | 1EVU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Saccharomyces |
| Primary Citation |
Tryptophan 279 is Essential for the Transglutaminase Activity of Coagulation Factor XIII: Functional and Structural Characterization
To Be Published
|