CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
| Superfamily | Immunoglobulins |
| Functional Family | MHC class II antigen |
Enzyme Information
| 4.1.1.15 |
Glutamate decarboxylase.
based on mapping to UniProt Q05329
L-glutamate = 4-aminobutanoate + CO(2).
-!- The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate.
|
UniProtKB Entries (2)
| P04228 |
HA2D_MOUSE
Mus musculus
H-2 class II histocompatibility antigen, A-D alpha chain
|
| Q05329 |
DCE2_HUMAN
Homo sapiens
Glutamate decarboxylase 2
|
PDB Structure
| PDB | 1ES0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes.
Science
|