PDB 4k8b

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PDB Links
Overview

PDB Information

PDB	4K8B
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Hepatitis C virus
Primary Citation	Ligand bioactive conformation plays a critical role in the design of drugs that target the hepatitis C virus NS3 protease. Laplante, S.R., Nar, H., Lemke, C.T., Jakalian, A., Aubry, N., Kawai, S.H. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-04-18
Resolution	2.800
CATH Insert Date	30 Mar, 2014

PDB Images (9)

Image of CATH 4k8b

4k8b

PDB 4k8b

Image of CATH 4k8bA

4k8bA

PDB Chain 4k8bA

Image of CATH 4k8bB

4k8bB

PDB Chain 4k8bB

Image of CATH 4k8bC

4k8bC

PDB Chain 4k8bC

Image of CATH 4k8bD

4k8bD

PDB Chain 4k8bD

Image of CATH 4k8bA01

4k8bA01

CATH Domain 4k8bA01

Image of CATH 4k8bA02

4k8bA02

CATH Domain 4k8bA02

Image of CATH 4k8bB01

4k8bB01

CATH Domain 4k8bB01

Image of CATH 4k8bB02

4k8bB02

CATH Domain 4k8bB02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	31 Mar, 2014	Chopped
B	31 Mar, 2014	Chopped
C	31 Mar, 2014	Rejected
D	31 Mar, 2014	Rejected

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4k8bA01	25 Apr, 2014	2.40.10.120	Assigned
4k8bA02	25 Apr, 2014	2.40.10.10	Assigned
4k8bB01	17 Apr, 2014	2.40.10.120	Assigned
4k8bB02	17 Apr, 2014	2.40.10.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease