PDB 4k8b
PDB Information
| PDB | 4K8B |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Hepatitis C virus |
| Primary Citation | Ligand bioactive conformation plays a critical role in the design of drugs that target the hepatitis C virus NS3 protease.
J.Med.Chem.
|
| Header | Hydrolase/Hydrolase Inhibitor |
| Released | 2013-04-18 |
| Resolution | 2.800 |
| CATH Insert Date | 30 Mar, 2014 |
PDB Prints
PDB Chains (4)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 31 Mar, 2014 | Chopped |
| B | 31 Mar, 2014 | Chopped |
| C | 31 Mar, 2014 | Rejected |
| D | 31 Mar, 2014 | Rejected |
CATH Domains (4)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4k8bA01 | 25 Apr, 2014 | 2.40.10.120 | Assigned |
| 4k8bA02 | 25 Apr, 2014 | 2.40.10.10 | Assigned |
| 4k8bB01 | 17 Apr, 2014 | 2.40.10.120 | Assigned |
| 4k8bB02 | 17 Apr, 2014 | 2.40.10.10 | Assigned |
UniProtKB Entries (4)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q0ZNA6 | Q0ZNA6_9HEPC | Hepacivirus C | NS3 protease |
| Q0ZNA6 | Q0ZNA6_9HEPC | Hepacivirus C | NS3 protease |
| P26663 | POLG_HCVBK | Hepatitis C virus (isolate BK) | Genome polyprotein |
| P26663 | POLG_HCVBK | Hepatitis C virus (isolate BK) | Genome polyprotein |
