CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
| Superfamily | Trypsin-like serine proteases |
| Functional Family | Genome polyprotein |
Enzyme Information
UniProtKB Entries (2)
| P26663 |
POLG_HCVBK
Hepatitis C virus (isolate BK)
Genome polyprotein
|
| Q0ZNA6 |
Q0ZNA6_9HEPC
Hepacivirus C
NS3 protease
|
PDB Structure
| PDB | 4K8B |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Ligand bioactive conformation plays a critical role in the design of drugs that target the hepatitis C virus NS3 protease.
J.Med.Chem.
|
