PDB 2q1l

PDB Information

PDB2Q1L
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors.
Pfefferkorn, J.A., Song, Y., Sun, K.L., Miller, S.R., Trivedi, B.K., Choi, C., Sorenson, R.J., Bratton, L.D., Unangst, P.C., Larsen, S.D., Poel, T.J., Cheng, X.M., Lee, C., Erasga, N., Auerbach, B., Askew, V., Dillon, L., Hanselman, J.C., Lin, Z., Lu, G., Robertson, A., Olsen, K., Mertz, T., Sekerke, C., Pavlovsky, A., Harris, M.S., Bainbridge, G., Caspers, N., Chen, H., Eberstadt, M.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase
Released2007-05-24
Resolution2.050
CATH Insert Date19 Jul, 2007

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 19 Jul, 2007 Chopped
B 19 Jul, 2007 Chopped
C 19 Jul, 2007 Chopped
D 19 Jul, 2007 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
2q1lA01 16 Aug, 2007 1.10.3270.10 Assigned
2q1lA02 16 Aug, 2007 3.90.770.10 Assigned
2q1lA03 16 Aug, 2007 3.30.70.420 Assigned
2q1lB01 16 Aug, 2007 1.10.3270.10 Assigned
2q1lB02 16 Aug, 2007 3.90.770.10 Assigned
2q1lB03 16 Aug, 2007 3.30.70.420 Assigned
2q1lC01 16 Aug, 2007 1.10.3270.10 Assigned
2q1lC02 16 Aug, 2007 3.90.770.10 Assigned
2q1lC03 16 Aug, 2007 3.30.70.420 Assigned
2q1lD01 16 Aug, 2007 1.10.3270.10 Assigned
2q1lD02 16 Aug, 2007 3.90.770.10 Assigned
2q1lD03 16 Aug, 2007 3.30.70.420 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase