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CATH Superfamily 3.30.70.420

Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain

This superfamily is made up of 2 alpha helices and 4 beta strands arranged into alpha-beta plaits.

Within Hydroxymethylglutaryl-CoA reductase, class I/II, this superfamily forms a domain which is implicated in binding NAD and NADP.

GO Diversity

Unique GO annotations
73 Unique GO terms

EC Diversity

Unique EC annotations
2 Unique EC terms

Species Diversity

Unique species annotations
2712 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 121
Domain clusters (>95% seq id): 4
Domain clusters (>35% seq id): 2
Unique PDBs: 38
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 6
Function
Unique EC: 2
Unique GO: 73
Taxonomy
Unique Species: 2712