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1 keywords

CATH Domain 6ct7B02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa constant

Enzyme Information

UniProtKB Entries (1)

P37840
SYUA_HUMAN
Homo sapiens
Alpha-synuclein

PDB Structure

PDB 6CT7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Development of an aggregate-selective, human-derived alpha-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models.
Weihofen, A., Liu, Y., Arndt, J.W., Huy, C., Quan, C., Smith, B.A., Baeriswyl, J.L., Cavegn, N., Senn, L., Su, L., Marsh, G., Auluck, P.K., Montrasio, F., Nitsch, R.M., Hirst, W.D., Cedarbaum, J.M., Pepinsky, R.B., Grimm, J., Weinreb, P.H.
Neurobiol. Dis.
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