CATH Domain 5x60A01

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family	Lysine-specific histone demethylase 1A

Enzyme Information

1.-.-.-

Oxidoreductases.

based on mapping to UniProt O60341

UniProtKB Entries (1)

H31_HUMAN

Homo sapiens

Histone H3.1

PDB Structure

PDB	5X60
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1. Amano, Y., Kikuchi, M., Sato, S., Yokoyama, S., Umehara, T., Umezawa, N., Higuchi, T. Bioorg. Med. Chem.