CATH Domain 4wk8G00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family	Forkhead box P2 isoform B

Enzyme Information

UniProtKB Entries (1)

FOXP3_HUMAN

Homo sapiens

Forkhead box protein P3

PDB Structure

PDB	4WK8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions. Chen, Y., Chen, C., Zhang, Z., Liu, C.C., Johnson, M.E., Espinoza, C.A., Edsall, L.E., Ren, B., Zhou, X.J., Grant, S.F., Wells, A.D., Chen, L. Nucleic Acids Res.