CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.565 | Heat Shock Protein 90 |
|
3.30.565.10 | Histidine kinase-like ATPase, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Histidine kinase-like ATPase, C-terminal domain |
| Functional Family | Two-component sensor kinase EnvZ |
Enzyme Information
| 2.7.13.3 |
Histidine kinase.
based on mapping to UniProt P0AEJ4
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
-!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.
|
UniProtKB Entries (2)
| P0AEJ4 |
ENVZ_ECOLI
Escherichia coli K-12
Osmolarity sensor protein EnvZ
|
| Q9WZV7 |
Q9WZV7_THEMA
Thermotoga maritima MSB8
Sensor histidine kinase
|
PDB Structure
| PDB | 4KP4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Visualizing autophosphorylation in histidine kinases.
Nat Commun
|
