CATH Domain 4jp4A00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.390	Collagenase (Catalytic Domain)
	3.40.390.10	Collagenase (Catalytic Domain)

Domain Context

CATH Clusters

Superfamily	Collagenase (Catalytic Domain)
Functional Family	Collagenase 3

Enzyme Information

3.4.24.-

Metalloendopeptidases.

based on mapping to UniProt P45452

UniProtKB Entries (1)

MMP13_HUMAN

Homo sapiens

Collagenase 3

PDB Structure

PDB	4JP4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Hydantoin based inhibitors of MMP13--discovery of AZD6605. De Savi, C., Waterson, D., Pape, A., Lamont, S., Hadley, E., Mills, M., Page, K.M., Bowyer, J., Maciewicz, R.A. Bioorg.Med.Chem.Lett.