CATH Domain 4dy7F01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.497	Antithrombin; Chain I, domain 2
	3.30.497.10	Antithrombin, subunit I, domain 2

Domain Context

CATH Clusters

Superfamily	Antithrombin, subunit I, domain 2
Functional Family	glia-derived nexin isoform X1

Enzyme Information

UniProtKB Entries (1)

GDN_HUMAN

Homo sapiens

Glia-derived nexin

PDB Structure

PDB	4DY7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism. Li, W., Huntington, J.A. Blood