CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate Aminotransferase, domain 1
Functional Family

Enzyme Information

2.3.1.47
8-amino-7-oxononanoate synthase.
based on mapping to UniProt A0QX65
Pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO(2) + holo-[acyl-carrier protein].
-!- The enzyme catalyzes the decarboxylative condensation of L-alanine and pimeloyl-[acyl-carrier protein], a key step in the pathway for biotin biosynthesis. -!- Pimeloyl-CoA can be used with lower efficiency.

UniProtKB Entries (1)

A0QX65
BIOF_MYCS2
Mycolicibacterium smegmatis MC2 155
8-amino-7-oxononanoate synthase

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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