CATH Domain 3hg4A02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1180	Golgi alpha-mannosidase II

Domain Context

CATH Clusters

Superfamily	Golgi alpha-mannosidase II
Functional Family	Alpha-galactosidase A

Enzyme Information

3.2.1.22

Alpha-galactosidase.

based on mapping to UniProt P06280

Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha- D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.

-!- Also hydrolyzes alpha-D-fucosides.

UniProtKB Entries (1)

P06280

AGAL_HUMAN

Homo sapiens

Alpha-galactosidase A

PDB Structure

PDB	3HG4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Catalytic mechanism of human alpha-galactosidase. Guce, A.I., Clark, N.E., Salgado, E.N., Ivanen, D.R., Kulminskaya, A.A., Brumer, H., Garman, S.C. J.Biol.Chem.