CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.390 | Collagenase (Catalytic Domain) |
|
3.40.390.10 | Collagenase (Catalytic Domain) |
Domain Context
CATH Clusters
| Superfamily | Collagenase (Catalytic Domain) |
| Functional Family | Disintegrin and metalloproteinase domain-containing protein 22 |
Enzyme Information
| 3.4.24.49 |
Bothropasin.
based on mapping to UniProt O93523
Cleavage of 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-15, 16-Tyr-|-Leu-17 and 24-Phe-|-Phe-25 in insulin B chain.
-!- Caseinolytic endopeptidase of jararaca snake (Bothrops jararaca) venom. -!- Belongs to peptidase family M12B.
|
UniProtKB Entries (1)
| O93523 |
VM3BP_BOTJA
Bothrops jararaca
Zinc metalloproteinase-disintegrin-like bothropasin
|
PDB Structure
| PDB | 3DSL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The three-dimensional structure of bothropasin, the main hemorrhagic factor from Bothrops jararaca venom: Insights for a new classification of snake venom metalloprotease subgroups.
Toxicon
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